(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-one

99%

  • Product Code: 246554
  Alias:    4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-A]pyrazine-7-(8H)-yl]-1-(2,4,5-trifluorophenyl)-2-butanone
  CAS:    764667-65-4
Molecular Weight: 406.28 g./mol Molecular Formula: C₁₆H₁₂F₆N₄O₂
EC Number: MDL Number:
Melting Point: 82-84°C Boiling Point: 513.902ºC at 760 mmHg
Density: Storage Condition: -20℃
Product Description: Used as a key intermediate in the synthesis of sitagliptin, a medication for type 2 diabetes. It plays a critical role in forming the core structure of the drug, enabling efficient inhibition of the DPP-4 enzyme, which helps regulate blood sugar levels. Its structure allows for high selectivity and potency in the final pharmaceutical product. Widely utilized in active pharmaceutical ingredient (API) manufacturing due to its stability and reactivity profile in multi-step synthesis.
Sizes / Availability / Pricing:
Size Availability Price Quantity
1g 10-20 days Ft2,864.90
+
-
5g 10-20 days Ft6,548.35
+
-
25g 10-20 days Ft32,332.49
+
-
100g 10-20 days Ft81,035.87
+
-
(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-one
Used as a key intermediate in the synthesis of sitagliptin, a medication for type 2 diabetes. It plays a critical role in forming the core structure of the drug, enabling efficient inhibition of the DPP-4 enzyme, which helps regulate blood sugar levels. Its structure allows for high selectivity and potency in the final pharmaceutical product. Widely utilized in active pharmaceutical ingredient (API) manufacturing due to its stability and reactivity profile in multi-step synthesis.
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