(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-one
99%
- Product Code: 246554
Alias:
4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-A]pyrazine-7-(8H)-yl]-1-(2,4,5-trifluorophenyl)-2-butanone
CAS:
764667-65-4
Molecular Weight: | 406.28 g./mol | Molecular Formula: | C₁₆H₁₂F₆N₄O₂ |
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EC Number: | MDL Number: | ||
Melting Point: | 82-84°C | Boiling Point: | 513.902ºC at 760 mmHg |
Density: | Storage Condition: | -20℃ |
Product Description:
Used as a key intermediate in the synthesis of sitagliptin, a medication for type 2 diabetes. It plays a critical role in forming the core structure of the drug, enabling efficient inhibition of the DPP-4 enzyme, which helps regulate blood sugar levels. Its structure allows for high selectivity and potency in the final pharmaceutical product. Widely utilized in active pharmaceutical ingredient (API) manufacturing due to its stability and reactivity profile in multi-step synthesis.
Sizes / Availability / Pricing:
Size | Availability | Price | Quantity |
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1g | 10-20 days | Ft2,864.90 |
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5g | 10-20 days | Ft6,548.35 |
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25g | 10-20 days | Ft32,332.49 |
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100g | 10-20 days | Ft81,035.87 |
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(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-one
Used as a key intermediate in the synthesis of sitagliptin, a medication for type 2 diabetes. It plays a critical role in forming the core structure of the drug, enabling efficient inhibition of the DPP-4 enzyme, which helps regulate blood sugar levels. Its structure allows for high selectivity and potency in the final pharmaceutical product. Widely utilized in active pharmaceutical ingredient (API) manufacturing due to its stability and reactivity profile in multi-step synthesis.
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