(Z)-5-(4-Hydroxybenzylidene)thiazolidine-2,4-dione
95%
- Product Code: 246742
CAS:
154052-92-3
| Molecular Weight: | 221.23 g./mol | Molecular Formula: | C₁₀H₇NO₃S |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00711076 | |
| Melting Point: | >300 °C | Boiling Point: | |
| Density: | 1.542±0.06 g/cm3(Predicted) | Storage Condition: | Room temperature |
Product Description:
Used in pharmaceutical research as a key scaffold for developing antidiabetic agents due to its structural similarity to thiazolidinediones, a class of insulin sensitizers. It serves as an intermediate in synthesizing compounds that target peroxisome proliferator-activated receptor gamma (PPARγ), which regulates glucose and lipid metabolism. Additionally, derivatives of this compound are explored for their antioxidant and anti-inflammatory properties, making them candidates for treating metabolic disorders and neurodegenerative diseases. Its (Z)-configuration is critical for biological activity, influencing binding affinity and potency in drug design.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | ฿5,500.00 |
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| 0.250 | 10-20 days | ฿9,910.00 |
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| 1.000 | 10-20 days | ฿20,410.00 |
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(Z)-5-(4-Hydroxybenzylidene)thiazolidine-2,4-dione
Used in pharmaceutical research as a key scaffold for developing antidiabetic agents due to its structural similarity to thiazolidinediones, a class of insulin sensitizers. It serves as an intermediate in synthesizing compounds that target peroxisome proliferator-activated receptor gamma (PPARγ), which regulates glucose and lipid metabolism. Additionally, derivatives of this compound are explored for their antioxidant and anti-inflammatory properties, making them candidates for treating metabolic disorders and neurodegenerative diseases. Its (Z)-configuration is critical for biological activity, influencing binding affinity and potency in drug design.
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