(Z-DEVD)2-R110
95%
- Product Code: 246779
CAS:
223538-61-2
| Molecular Weight: | 1515.46 g./mol | Molecular Formula: | C₇₂H₇₈N₁₀O₂₇ |
|---|---|---|---|
| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20°C, avoiding light |
Product Description:
Used as a fluorescent substrate for detecting caspase-3 and caspase-7 activity in apoptosis assays. The compound becomes fluorescent upon cleavage by these enzymes, allowing real-time monitoring of programmed cell death in live cells or cell lysates. Commonly applied in high-throughput screening for drug discovery, toxicology studies, and research on cellular death pathways. Its Z-DEVD sequence is specifically recognized by caspase-3/7, ensuring high selectivity. The R110 (rhodamine 110) moiety provides a strong fluorescent signal after enzymatic cleavage, making it suitable for fluorometric detection methods.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 0.001 | 10-20 days | ฿20,980.00 |
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(Z-DEVD)2-R110
Used as a fluorescent substrate for detecting caspase-3 and caspase-7 activity in apoptosis assays. The compound becomes fluorescent upon cleavage by these enzymes, allowing real-time monitoring of programmed cell death in live cells or cell lysates. Commonly applied in high-throughput screening for drug discovery, toxicology studies, and research on cellular death pathways. Its Z-DEVD sequence is specifically recognized by caspase-3/7, ensuring high selectivity. The R110 (rhodamine 110) moiety provides a strong fluorescent signal after enzymatic cleavage, making it suitable for fluorometric detection methods.
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