(Z)-N'-hydroxy-2-(2-nitrophenyl)acetimidamide
97%
- Product Code: 246870
CAS:
154224-24-5
| Molecular Weight: | 195.18 g./mol | Molecular Formula: | C₈H₉N₃O₃ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00245242 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | Room temperature |
Product Description:
Used primarily in biochemical and pharmaceutical research as a potent inhibitor of matrix metalloproteinases (MMPs), particularly MMP-2 and MMP-9. These enzymes are involved in the degradation of extracellular matrix components and play key roles in cancer metastasis, inflammation, and tissue remodeling. The compound’s hydroxamic acid-like structure enables strong chelation of zinc ions at the active site of MMPs, making it an effective scaffold in the development of anticancer and anti-inflammatory agents. It is also employed in studies related to angiogenesis and tumor progression due to its ability to modulate cell invasion and migration. Its (Z)-configuration is critical for optimal binding and inhibitory activity.
Sizes / Availability / Pricing:
| Size | Availability | Price | Quantity |
|---|---|---|---|
| 1g | 10-20 days | ฿5,000.00 |
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| 5g | 10-20 days | ฿15,260.00 |
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(Z)-N'-hydroxy-2-(2-nitrophenyl)acetimidamide
Used primarily in biochemical and pharmaceutical research as a potent inhibitor of matrix metalloproteinases (MMPs), particularly MMP-2 and MMP-9. These enzymes are involved in the degradation of extracellular matrix components and play key roles in cancer metastasis, inflammation, and tissue remodeling. The compound’s hydroxamic acid-like structure enables strong chelation of zinc ions at the active site of MMPs, making it an effective scaffold in the development of anticancer and anti-inflammatory agents. It is also employed in studies related to angiogenesis and tumor progression due to its ability to modulate cell invasion and migration. Its (Z)-configuration is critical for optimal binding and inhibitory activity.
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