(1R,2R)-N1,N1-Bis(2-(di-p-tolylphosphino)benzyl)cyclohexane-1,2-diamine
98%,99%ee
- Product Code: 36203
CAS:
1150113-65-7
| Molecular Weight: | 718.8874 g./mol | Molecular Formula: | C₄₈H₅₂N₂P₂ |
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| EC Number: | MDL Number: | MFCD17014023 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8°C |
Product Description:
This chemical is primarily used as a chiral ligand in asymmetric catalysis, particularly in transition metal-catalyzed reactions. Its application is significant in the synthesis of enantiomerically pure compounds, which are crucial in the pharmaceutical industry for producing drugs with high stereochemical purity. The ligand's structure, featuring phosphine and diamine groups, allows it to effectively coordinate with metals like rhodium, iridium, or palladium, enabling highly selective transformations such as hydrogenation, hydroformylation, or cross-coupling reactions. Its use is particularly valuable in creating chiral intermediates for active pharmaceutical ingredients (APIs), where the correct stereochemistry is essential for biological activity. Additionally, it finds utility in academic research for developing new catalytic methodologies and exploring stereoselective synthesis pathways.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | ฿2,187.00 |
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(1R,2R)-N1,N1-Bis(2-(di-p-tolylphosphino)benzyl)cyclohexane-1,2-diamine
This chemical is primarily used as a chiral ligand in asymmetric catalysis, particularly in transition metal-catalyzed reactions. Its application is significant in the synthesis of enantiomerically pure compounds, which are crucial in the pharmaceutical industry for producing drugs with high stereochemical purity. The ligand's structure, featuring phosphine and diamine groups, allows it to effectively coordinate with metals like rhodium, iridium, or palladium, enabling highly selective transformations such as hydrogenation, hydroformylation, or cross-coupling reactions. Its use is particularly valuable in creating chiral intermediates for active pharmaceutical ingredients (APIs), where the correct stereochemistry is essential for biological activity. Additionally, it finds utility in academic research for developing new catalytic methodologies and exploring stereoselective synthesis pathways.
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