tert-Butyl (2-iodopyridin-4-yl)carbamate
97%
- Product Code: 36449
CAS:
869735-25-1
| Molecular Weight: | 320.1300 g./mol | Molecular Formula: | C₁₀H₁₃IN₂O₂ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD08235127 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | room temperature |
Product Description:
tert-Butyl (2-iodopyridin-4-yl)carbamate is primarily used in organic synthesis as a versatile intermediate for the preparation of more complex chemical compounds. Its structure, featuring both a carbamate group and an iodine substituent on a pyridine ring, makes it particularly useful in cross-coupling reactions, such as Suzuki-Miyaura or Sonogashira couplings, which are essential in the synthesis of pharmaceuticals, agrochemicals, and advanced materials. The iodine atom serves as a reactive site for metal-catalyzed reactions, enabling the introduction of various functional groups or the formation of carbon-carbon bonds. Additionally, the tert-butyl carbamate group can act as a protecting group for amines, allowing selective reactions to occur elsewhere in the molecule before being removed under mild conditions. This compound is also valuable in medicinal chemistry for the development of drug candidates, particularly in the synthesis of heterocyclic compounds that exhibit biological activity. Its stability and reactivity make it a key building block in the construction of complex molecular architectures.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | ฿4,914.00 |
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tert-Butyl (2-iodopyridin-4-yl)carbamate
tert-Butyl (2-iodopyridin-4-yl)carbamate is primarily used in organic synthesis as a versatile intermediate for the preparation of more complex chemical compounds. Its structure, featuring both a carbamate group and an iodine substituent on a pyridine ring, makes it particularly useful in cross-coupling reactions, such as Suzuki-Miyaura or Sonogashira couplings, which are essential in the synthesis of pharmaceuticals, agrochemicals, and advanced materials. The iodine atom serves as a reactive site for metal-catalyzed reactions, enabling the introduction of various functional groups or the formation of carbon-carbon bonds. Additionally, the tert-butyl carbamate group can act as a protecting group for amines, allowing selective reactions to occur elsewhere in the molecule before being removed under mild conditions. This compound is also valuable in medicinal chemistry for the development of drug candidates, particularly in the synthesis of heterocyclic compounds that exhibit biological activity. Its stability and reactivity make it a key building block in the construction of complex molecular architectures.
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