(2R,4S)-4-Amino-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid

≥95%

  • Product Code: 36493
  CAS:    132622-78-7
Molecular Weight: 230.26 g./mol Molecular Formula: C₁₀H₁₈N₂O₄
EC Number: MDL Number: MFCD08704543
Melting Point: Boiling Point: 371.073°C at 760 mmHg
Density: 1.233g/cm3 Storage Condition: 2-8°C, dry and sealed
Product Description: This compound is primarily utilized in the synthesis of peptides and peptidomimetics, serving as a key building block in the development of pharmaceutical agents. Its structure, featuring both a protected amine group (tert-butoxycarbonyl) and a carboxylic acid, makes it valuable in solid-phase peptide synthesis (SPPS). It is often employed to introduce specific chiral centers into peptide chains, enhancing the biological activity and stability of the final product. Additionally, it is used in the preparation of proline analogs, which are crucial in drug discovery for targeting enzymes and receptors involved in various diseases. Its role in creating constrained peptides also aids in improving pharmacokinetic properties, such as bioavailability and metabolic stability.
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
0.100 10-20 days ฿2,853.00
+
-
0.250 10-20 days ฿4,671.00
+
-
1.000 10-20 days ฿9,729.00
+
-
5.000 10-20 days ฿40,185.00
+
-
(2R,4S)-4-Amino-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid
This compound is primarily utilized in the synthesis of peptides and peptidomimetics, serving as a key building block in the development of pharmaceutical agents. Its structure, featuring both a protected amine group (tert-butoxycarbonyl) and a carboxylic acid, makes it valuable in solid-phase peptide synthesis (SPPS). It is often employed to introduce specific chiral centers into peptide chains, enhancing the biological activity and stability of the final product. Additionally, it is used in the preparation of proline analogs, which are crucial in drug discovery for targeting enzymes and receptors involved in various diseases. Its role in creating constrained peptides also aids in improving pharmacokinetic properties, such as bioavailability and metabolic stability.
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