(2R,4S)-4-Amino-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid
≥95%
- Product Code: 36493
CAS:
132622-78-7
| Molecular Weight: | 230.26 g./mol | Molecular Formula: | C₁₀H₁₈N₂O₄ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD08704543 | |
| Melting Point: | Boiling Point: | 371.073°C at 760 mmHg | |
| Density: | 1.233g/cm3 | Storage Condition: | 2-8°C, dry and sealed |
Product Description:
This compound is primarily utilized in the synthesis of peptides and peptidomimetics, serving as a key building block in the development of pharmaceutical agents. Its structure, featuring both a protected amine group (tert-butoxycarbonyl) and a carboxylic acid, makes it valuable in solid-phase peptide synthesis (SPPS). It is often employed to introduce specific chiral centers into peptide chains, enhancing the biological activity and stability of the final product. Additionally, it is used in the preparation of proline analogs, which are crucial in drug discovery for targeting enzymes and receptors involved in various diseases. Its role in creating constrained peptides also aids in improving pharmacokinetic properties, such as bioavailability and metabolic stability.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | $118.48 |
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| 0.250 | 10-20 days | $193.98 |
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| 1.000 | 10-20 days | $404.04 |
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| 5.000 | 10-20 days | $1,668.84 |
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(2R,4S)-4-Amino-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid
This compound is primarily utilized in the synthesis of peptides and peptidomimetics, serving as a key building block in the development of pharmaceutical agents. Its structure, featuring both a protected amine group (tert-butoxycarbonyl) and a carboxylic acid, makes it valuable in solid-phase peptide synthesis (SPPS). It is often employed to introduce specific chiral centers into peptide chains, enhancing the biological activity and stability of the final product. Additionally, it is used in the preparation of proline analogs, which are crucial in drug discovery for targeting enzymes and receptors involved in various diseases. Its role in creating constrained peptides also aids in improving pharmacokinetic properties, such as bioavailability and metabolic stability.
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