Methyl (3R)-3-(tert-butyldimethylsilyloxy)-5-oxo-6-triphenylphosphoranylidenehexanoate
98%
- Product Code: 36742
CAS:
147118-35-2
| Molecular Weight: | 534.71 g./mol | Molecular Formula: | C₃₁H₃₉O₄PSi |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD09753068 | |
| Melting Point: | 77.5-78.5°C | Boiling Point: | 603.9°C |
| Density: | 1.1g/mL | Storage Condition: | room temperature, dry |
Product Description:
This chemical is primarily used in organic synthesis as a key intermediate in the preparation of complex molecules, particularly in the field of pharmaceuticals and natural product synthesis. Its structure, featuring a tert-butyldimethylsilyl (TBDMS) protecting group and a phosphoranylidene moiety, makes it valuable for selective reactions, such as the Wittig reaction, which is widely employed to form alkenes. The TBDMS group protects the hydroxyl functionality during multi-step synthetic processes, ensuring the integrity of the molecule until deprotection is required. Additionally, the compound is often utilized in the synthesis of biologically active compounds, including steroids and other polyfunctional molecules, due to its ability to facilitate precise control over stereochemistry and functional group transformations. Its application is particularly significant in the development of drugs targeting specific biological pathways, where the introduction of double bonds or specific chiral centers is critical for activity.
Product Specification:
| Test | Specification |
|---|---|
| APPEARANCE | Light yellow to yellow powder or crystals |
| PURITY | 97.5-100 |
| Infrared spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 1.000 | 10-20 days | £22.39 |
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| 5.000 | 10-20 days | £109.01 |
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Methyl (3R)-3-(tert-butyldimethylsilyloxy)-5-oxo-6-triphenylphosphoranylidenehexanoate
This chemical is primarily used in organic synthesis as a key intermediate in the preparation of complex molecules, particularly in the field of pharmaceuticals and natural product synthesis. Its structure, featuring a tert-butyldimethylsilyl (TBDMS) protecting group and a phosphoranylidene moiety, makes it valuable for selective reactions, such as the Wittig reaction, which is widely employed to form alkenes. The TBDMS group protects the hydroxyl functionality during multi-step synthetic processes, ensuring the integrity of the molecule until deprotection is required. Additionally, the compound is often utilized in the synthesis of biologically active compounds, including steroids and other polyfunctional molecules, due to its ability to facilitate precise control over stereochemistry and functional group transformations. Its application is particularly significant in the development of drugs targeting specific biological pathways, where the introduction of double bonds or specific chiral centers is critical for activity.
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