4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrazole
≥95%
- Product Code: 39543
CAS:
894807-98-8
| Molecular Weight: | 324.30 g./mol | Molecular Formula: | C₁₅H₂₉BN₂O₃Si |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD20486100 | |
| Melting Point: | Boiling Point: | 395.1±27.0°C at 760 mmHg | |
| Density: | Storage Condition: | 2-8°C, store under inert gas |
Product Description:
This compound is primarily utilized in organic synthesis, particularly in cross-coupling reactions such as the Suzuki-Miyaura reaction, where it acts as a boronic ester reagent. The presence of the dioxaborolane group enables efficient coupling with aryl or vinyl halides, facilitating the formation of carbon-carbon bonds. The trimethylsilylethoxymethyl (SEM) protecting group attached to the pyrazole nitrogen enhances stability during reactions, making it suitable for multi-step synthetic processes. It is commonly employed in the pharmaceutical and agrochemical industries for the development of complex molecules, including drug intermediates and active ingredients. Additionally, its structural features make it valuable in material science for creating functionalized polymers and advanced organic materials.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
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| 0.100 | 10-20 days | £151.85 |
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| 0.250 | 10-20 days | £227.78 |
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| 1.000 | 10-20 days | £569.54 |
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4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-pyrazole
This compound is primarily utilized in organic synthesis, particularly in cross-coupling reactions such as the Suzuki-Miyaura reaction, where it acts as a boronic ester reagent. The presence of the dioxaborolane group enables efficient coupling with aryl or vinyl halides, facilitating the formation of carbon-carbon bonds. The trimethylsilylethoxymethyl (SEM) protecting group attached to the pyrazole nitrogen enhances stability during reactions, making it suitable for multi-step synthetic processes. It is commonly employed in the pharmaceutical and agrochemical industries for the development of complex molecules, including drug intermediates and active ingredients. Additionally, its structural features make it valuable in material science for creating functionalized polymers and advanced organic materials.
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