1-Boc-3-Bromo-5-methoxyindole
98%
- Product Code: 45291
CAS:
348640-11-9
| Molecular Weight: | 326.19 g./mol | Molecular Formula: | C₁₄H₁₆BrNO₃ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD05864762 | |
| Melting Point: | Boiling Point: | 403.846ºC | |
| Density: | 1.379g/cm3 | Storage Condition: | Room temperature, dry, sealed |
Product Description:
This compound is widely used in organic synthesis, particularly in the pharmaceutical and agrochemical industries. It serves as a key intermediate in the production of various biologically active molecules, including drug candidates and agrochemicals. The Boc (tert-butoxycarbonyl) group provides protection for the indole nitrogen during synthetic processes, allowing for selective reactions at other sites of the molecule. The bromine atom at the 3-position offers a reactive site for further functionalization through cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings, enabling the introduction of diverse substituents. The methoxy group at the 5-position can influence the electronic properties of the indole ring, enhancing its reactivity or modulating the biological activity of the final product. This compound is particularly valuable in the synthesis of indole-based alkaloids, serotonin receptor ligands, and other heterocyclic compounds with potential therapeutic applications. Its versatility makes it a crucial building block in medicinal chemistry and drug discovery.
Product Specification:
| Test | Specification |
|---|---|
| Purity | 97.5-100 |
| Appearance | Off-white powder |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | ฿1,240.00 |
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| 0.500 | 10-20 days | ฿2,590.00 |
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| 2.000 | 10-20 days | ฿10,060.00 |
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1-Boc-3-Bromo-5-methoxyindole
This compound is widely used in organic synthesis, particularly in the pharmaceutical and agrochemical industries. It serves as a key intermediate in the production of various biologically active molecules, including drug candidates and agrochemicals. The Boc (tert-butoxycarbonyl) group provides protection for the indole nitrogen during synthetic processes, allowing for selective reactions at other sites of the molecule. The bromine atom at the 3-position offers a reactive site for further functionalization through cross-coupling reactions, such as Suzuki or Buchwald-Hartwig couplings, enabling the introduction of diverse substituents. The methoxy group at the 5-position can influence the electronic properties of the indole ring, enhancing its reactivity or modulating the biological activity of the final product. This compound is particularly valuable in the synthesis of indole-based alkaloids, serotonin receptor ligands, and other heterocyclic compounds with potential therapeutic applications. Its versatility makes it a crucial building block in medicinal chemistry and drug discovery.
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