4-[(5-aza-3,4:7,8-dibenzocyclooctan-1-yne)-5-yl]-4-oxobutyrate-n-succinimide
98%
- Product Code: 46728
CAS:
1353016-71-3
| Molecular Weight: | 402.40 g./mol | Molecular Formula: | C₂₃H₁₈N₂O₅ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD24386367 | |
| Melting Point: | Boiling Point: | 670.2±65.0 °C at 760 mmHg | |
| Density: | 1.43±0.1 g/cm3 | Storage Condition: | 2-8℃ |
Product Description:
This chemical is primarily utilized in bioconjugation and protein labeling due to its reactive succinimide ester group, which facilitates covalent bonding with primary amines in proteins, peptides, and other biomolecules. It is particularly valuable in the development of antibody-drug conjugates (ADCs) for targeted cancer therapies, where it enables the precise attachment of cytotoxic agents to antibodies. Additionally, it is employed in fluorescence labeling for imaging and diagnostic applications, allowing researchers to track and visualize biological processes in real-time. Its unique structure also makes it suitable for crosslinking studies in biochemistry, aiding in the investigation of protein-protein interactions and molecular structures.
Product Specification:
| Test | Specification |
|---|---|
| APPEARANCE | White to off-white Solid |
| PURITY | 97.5-100 |
| Infrared spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.050 | 10-20 days | Ft100,414.69 |
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| 0.100 | 10-20 days | Ft149,652.36 |
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4-[(5-aza-3,4:7,8-dibenzocyclooctan-1-yne)-5-yl]-4-oxobutyrate-n-succinimide
This chemical is primarily utilized in bioconjugation and protein labeling due to its reactive succinimide ester group, which facilitates covalent bonding with primary amines in proteins, peptides, and other biomolecules. It is particularly valuable in the development of antibody-drug conjugates (ADCs) for targeted cancer therapies, where it enables the precise attachment of cytotoxic agents to antibodies. Additionally, it is employed in fluorescence labeling for imaging and diagnostic applications, allowing researchers to track and visualize biological processes in real-time. Its unique structure also makes it suitable for crosslinking studies in biochemistry, aiding in the investigation of protein-protein interactions and molecular structures.
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