5'-O-DMT-2'-TBDMS-Uridine
97%
- Product Code: 47928
CAS:
81246-80-2
| Molecular Weight: | 660.83 g./mol | Molecular Formula: | C₃₆H₄₄N₂O₈Si |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00135726 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8°C, store under inert gas |
Product Description:
Used primarily in oligonucleotide synthesis, it serves as a protected nucleoside to ensure selective reactivity during the formation of RNA strands. The DMT (dimethoxytrityl) group protects the 5'-hydroxyl, while the TBDMS (tert-butyldimethylsilyl) group shields the 2'-hydroxyl, allowing precise control over the assembly of RNA sequences. This compound is critical in the production of synthetic RNA for research, therapeutics, and diagnostics, including applications in siRNA, antisense oligonucleotides, and mRNA vaccines. Its protective groups are later removed under specific conditions to yield the desired RNA product.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.250 | 10-20 days | ฿2,250.00 |
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| 1.000 | 10-20 days | ฿4,284.00 |
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| 5.000 | 10-20 days | ฿15,030.00 |
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5'-O-DMT-2'-TBDMS-Uridine
Used primarily in oligonucleotide synthesis, it serves as a protected nucleoside to ensure selective reactivity during the formation of RNA strands. The DMT (dimethoxytrityl) group protects the 5'-hydroxyl, while the TBDMS (tert-butyldimethylsilyl) group shields the 2'-hydroxyl, allowing precise control over the assembly of RNA sequences. This compound is critical in the production of synthetic RNA for research, therapeutics, and diagnostics, including applications in siRNA, antisense oligonucleotides, and mRNA vaccines. Its protective groups are later removed under specific conditions to yield the desired RNA product.
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