5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyluridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite

≥95%

  • Product Code: 47933
  CAS:    110764-79-9
Molecular Weight: 760.81 g./mol Molecular Formula: C₄₀H₄₉N₄O₉P
EC Number: MDL Number: MFCD00792626
Melting Point: Boiling Point:
Density: Storage Condition: 2-8°C, dry and sealed
Product Description: This compound is primarily used in the synthesis of oligonucleotides, particularly in the field of molecular biology and genetic research. It serves as a key building block in solid-phase oligonucleotide synthesis, where it is employed to introduce 2'-O-methyluridine residues into RNA sequences. The 4,4'-dimethoxytrityl (DMT) group protects the 5'-hydroxyl during synthesis, while the 2-cyanoethyl and diisopropyl groups on the phosphoramidite moiety ensure efficient coupling reactions. Its application is crucial in creating modified RNA molecules for therapeutic purposes, such as antisense oligonucleotides, siRNA, and other RNA-based therapeutics, where enhanced stability and specificity are required. Additionally, it is utilized in the development of diagnostic probes and tools for studying gene function and regulation.
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
1.000 10-20 days $70.43
+
-
5.000 10-20 days $257.66
+
-
10.000 10-20 days $458.34
+
-
5'-O-(4,4'-Dimethoxytrityl)-2'-O-methyluridine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
This compound is primarily used in the synthesis of oligonucleotides, particularly in the field of molecular biology and genetic research. It serves as a key building block in solid-phase oligonucleotide synthesis, where it is employed to introduce 2'-O-methyluridine residues into RNA sequences. The 4,4'-dimethoxytrityl (DMT) group protects the 5'-hydroxyl during synthesis, while the 2-cyanoethyl and diisopropyl groups on the phosphoramidite moiety ensure efficient coupling reactions. Its application is crucial in creating modified RNA molecules for therapeutic purposes, such as antisense oligonucleotides, siRNA, and other RNA-based therapeutics, where enhanced stability and specificity are required. Additionally, it is utilized in the development of diagnostic probes and tools for studying gene function and regulation.
Mechanism -
Appearance -
Longevity -
Strength -
Storage -
Shelf Life -
Allergen(s) -
Dosage (Range) -
Dosage (Per Day) -
Mix Method -
Heat Resistance -
Stable in pH range -
Solubility -
Product Types -
INCI -

Cart

No products

Subtotal: $0.00
$0.00 Total :

The availability date depends on real-time stock, and any changes after payment will be notified within 30 minutes
You can choose the delivery date on the next page