5'-O-DMT-N6-iBu-dA

97%

  • Product Code: 47937
  CAS:    190834-10-7
Molecular Weight: 623.71 g./mol Molecular Formula: C₃₅H₃₇N₅O₆
EC Number: MDL Number:
Melting Point: Boiling Point:
Density: Storage Condition: 2-8℃
Product Description: This chemical is primarily used in the field of oligonucleotide synthesis, particularly in the production of modified DNA strands. It serves as a protected nucleoside monomer, where the 5'-hydroxyl group is protected by a dimethoxytrityl (DMT) group, and the N6 position of the adenine base is modified with an isobutyl group. This protection strategy allows for controlled and sequential addition of nucleotides during solid-phase synthesis, ensuring high precision in the construction of custom DNA sequences. It is especially valuable in the development of therapeutic oligonucleotides, such as antisense molecules, siRNAs, and aptamers, which are used in gene silencing, targeted therapy, and diagnostic applications. The modifications enhance the stability and specificity of the synthesized oligonucleotides, making them more effective in biological systems.
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
0.010 10-20 days £93.23
+
-
0.050 10-20 days £325.68
+
-
5'-O-DMT-N6-iBu-dA
This chemical is primarily used in the field of oligonucleotide synthesis, particularly in the production of modified DNA strands. It serves as a protected nucleoside monomer, where the 5'-hydroxyl group is protected by a dimethoxytrityl (DMT) group, and the N6 position of the adenine base is modified with an isobutyl group. This protection strategy allows for controlled and sequential addition of nucleotides during solid-phase synthesis, ensuring high precision in the construction of custom DNA sequences. It is especially valuable in the development of therapeutic oligonucleotides, such as antisense molecules, siRNAs, and aptamers, which are used in gene silencing, targeted therapy, and diagnostic applications. The modifications enhance the stability and specificity of the synthesized oligonucleotides, making them more effective in biological systems.
Mechanism -
Appearance -
Longevity -
Strength -
Storage -
Shelf Life -
Allergen(s) -
Dosage (Range) -
Dosage (Per Day) -
Mix Method -
Heat Resistance -
Stable in pH range -
Solubility -
Product Types -
INCI -

Cart

No products

Subtotal: £0.00
£0.00 Total :

The availability date depends on real-time stock, and any changes after payment will be notified within 30 minutes
You can choose the delivery date on the next page