(5-(N-(tert-Butyl)sulfamoyl)-2-methoxyphenyl)boronic acid

95%

  • Product Code: 48333
  CAS:    731016-02-7
Molecular Weight: 287.14 g./mol Molecular Formula: C₁₁H₁₈BNO₅S
EC Number: MDL Number: MFCD20275287
Melting Point: Boiling Point:
Density: Storage Condition: room temperature
Product Description: This compound is primarily used in organic synthesis as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in the construction of complex molecules. Its boronic acid group is essential for coupling with aryl or vinyl halides, making it valuable in the synthesis of pharmaceuticals, agrochemicals, and advanced materials. The tert-butyl sulfamoyl moiety provides steric and electronic effects, which can enhance selectivity and stability in reactions. Additionally, the methoxy group may improve solubility or influence the reactivity of the compound. It is also employed in medicinal chemistry as a building block for designing drug candidates, particularly those targeting enzymes or receptors where the sulfamoyl and boronic acid functionalities can play a role in binding interactions.
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
0.250 10-20 days £184.22
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1.000 10-20 days £498.30
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(5-(N-(tert-Butyl)sulfamoyl)-2-methoxyphenyl)boronic acid
This compound is primarily used in organic synthesis as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the formation of carbon-carbon bonds in the construction of complex molecules. Its boronic acid group is essential for coupling with aryl or vinyl halides, making it valuable in the synthesis of pharmaceuticals, agrochemicals, and advanced materials. The tert-butyl sulfamoyl moiety provides steric and electronic effects, which can enhance selectivity and stability in reactions. Additionally, the methoxy group may improve solubility or influence the reactivity of the compound. It is also employed in medicinal chemistry as a building block for designing drug candidates, particularly those targeting enzymes or receptors where the sulfamoyl and boronic acid functionalities can play a role in binding interactions.
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