5-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-fluoro-b-D-arabinofuranosyl-2'-deoxyadenine
97%
- Product Code: 48442
CAS:
226415-08-3
| Molecular Weight: | 675.7 g./mol | Molecular Formula: | C₃₈H₃₄FN₅O₆ |
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| EC Number: | MDL Number: | MFCD15145200 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8℃ |
Product Description:
This compound is primarily used in the synthesis of oligonucleotides, particularly in the field of molecular biology and genetic research. Its role is crucial in the preparation of modified DNA strands, where the 2'-fluoro modification enhances the stability and binding affinity of the oligonucleotides. The dimethoxytrityl (DMT) group serves as a protective group during the synthesis process, allowing for selective deprotection and elongation of the oligonucleotide chain. The benzoyl group protects the adenine base, ensuring the correct sequence assembly. This chemical is instrumental in developing therapeutic oligonucleotides, such as antisense drugs and siRNA, which are used to target and modulate gene expression in various diseases. Additionally, its application extends to diagnostic tools, where it aids in the creation of probes for detecting specific genetic sequences.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 1.000 | 10-20 days | ฿139,293.00 |
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5-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-fluoro-b-D-arabinofuranosyl-2'-deoxyadenine
This compound is primarily used in the synthesis of oligonucleotides, particularly in the field of molecular biology and genetic research. Its role is crucial in the preparation of modified DNA strands, where the 2'-fluoro modification enhances the stability and binding affinity of the oligonucleotides. The dimethoxytrityl (DMT) group serves as a protective group during the synthesis process, allowing for selective deprotection and elongation of the oligonucleotide chain. The benzoyl group protects the adenine base, ensuring the correct sequence assembly. This chemical is instrumental in developing therapeutic oligonucleotides, such as antisense drugs and siRNA, which are used to target and modulate gene expression in various diseases. Additionally, its application extends to diagnostic tools, where it aids in the creation of probes for detecting specific genetic sequences.
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