6-(Pyridin-3-yl)pyrimidin-4-amine
97%
- Product Code: 49496
CAS:
1192814-34-8
| Molecular Weight: | 172.19 g./mol | Molecular Formula: | C₉H₈N₄ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD21234637 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8°C, dry and sealed away from light |
Product Description:
6-(Pyridin-3-yl)pyrimidin-4-amine finds significant application in the field of medicinal chemistry, particularly in the development of kinase inhibitors. Its structure is often utilized as a core scaffold in designing compounds that target specific kinases involved in various diseases, including cancer and inflammatory disorders. The compound's ability to interact with ATP-binding sites of kinases makes it a valuable building block for creating potent and selective inhibitors.
In drug discovery, this chemical is employed in the synthesis of small molecule therapeutics aimed at modulating signaling pathways that are dysregulated in pathological conditions. Its pyrimidine and pyridine moieties contribute to its binding affinity and specificity, making it a versatile intermediate for optimizing drug candidates. Additionally, it is used in biochemical assays to study kinase activity and to screen for potential drug leads.
Beyond its role in drug development, 6-(Pyridin-3-yl)pyrimidin-4-amine is also explored in academic research for understanding the structural and functional aspects of kinase proteins. Its applications extend to the design of probes and tools for investigating cellular signaling mechanisms, providing insights into disease biology and therapeutic interventions.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | ฿2,736.00 |
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| 0.250 | 10-20 days | ฿5,481.00 |
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6-(Pyridin-3-yl)pyrimidin-4-amine
6-(Pyridin-3-yl)pyrimidin-4-amine finds significant application in the field of medicinal chemistry, particularly in the development of kinase inhibitors. Its structure is often utilized as a core scaffold in designing compounds that target specific kinases involved in various diseases, including cancer and inflammatory disorders. The compound's ability to interact with ATP-binding sites of kinases makes it a valuable building block for creating potent and selective inhibitors.
In drug discovery, this chemical is employed in the synthesis of small molecule therapeutics aimed at modulating signaling pathways that are dysregulated in pathological conditions. Its pyrimidine and pyridine moieties contribute to its binding affinity and specificity, making it a versatile intermediate for optimizing drug candidates. Additionally, it is used in biochemical assays to study kinase activity and to screen for potential drug leads.
Beyond its role in drug development, 6-(Pyridin-3-yl)pyrimidin-4-amine is also explored in academic research for understanding the structural and functional aspects of kinase proteins. Its applications extend to the design of probes and tools for investigating cellular signaling mechanisms, providing insights into disease biology and therapeutic interventions.
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