Guanidine Hydrochloride

99% Biotech Grade

  • Product Code: 52115
  CAS:    50-01-1
Molecular Weight: 95.53 g./mol Molecular Formula: CH₅N₃HCl
EC Number: 200-002-3 MDL Number: MFCD00013026
Melting Point: 180-185 °C(lit.) Boiling Point:
Density: 1.345 g/cm3 at 20 °C(lit.) Storage Condition: room temperature
Product Description:

Guanidine hydrochloride is widely used in molecular biology for protein denaturation. It helps in breaking down the secondary and tertiary structures of proteins, making it useful in studies involving protein folding and unfolding. In biochemistry, it serves as a chaotropic agent, aiding in the solubilization of proteins and nucleic acids, particularly in extraction and purification processes. It is also employed in the preparation of RNA and DNA, where it helps in the isolation of these molecules by disrupting cell membranes and inactivating nucleases. Additionally, guanidine hydrochloride finds application in the treatment of certain medical conditions, such as myasthenia gravis, where it acts as a neuromuscular blocking agent. In industrial settings, it is used in the synthesis of various organic compounds, including pharmaceuticals and dyes, due to its strong basic properties.

Product Specification:
Test Specification
Melting point 180 189?
Purity 99 100%
APPEARANCE WHITE TO LIGHT YELLOW POWDER
Solubility Color Colorless
Solubility Turbidity 6M in H2O (286 g to 500 ml),Clear
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
100.000 10-20 days €10.82
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500.000 10-20 days €32.45
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2500.000 10-20 days €153.02
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Guanidine Hydrochloride

Guanidine hydrochloride is widely used in molecular biology for protein denaturation. It helps in breaking down the secondary and tertiary structures of proteins, making it useful in studies involving protein folding and unfolding. In biochemistry, it serves as a chaotropic agent, aiding in the solubilization of proteins and nucleic acids, particularly in extraction and purification processes. It is also employed in the preparation of RNA and DNA, where it helps in the isolation of these molecules by disrupting cell membranes and inactivating nucleases. Additionally, guanidine hydrochloride finds application in the treatment of certain medical conditions, such as myasthenia gravis, where it acts as a neuromuscular blocking agent. In industrial settings, it is used in the synthesis of various organic compounds, including pharmaceuticals and dyes, due to its strong basic properties.

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