Maleimide-PEG12-succinimidyl ester
- Product Code: 53384
CAS:
1426151-00-9
| Molecular Weight: | 865.92 g./mol | Molecular Formula: | C₃₈H₆₃N₃O₁₉ |
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| EC Number: | MDL Number: | MFCD11041148 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20 °C, sealed, dry, inflated |
Product Description:
Used primarily in bioconjugation, this chemical serves as a linker to attach biomolecules like proteins, peptides, or antibodies to other entities, such as nanoparticles or surfaces. Its PEG spacer enhances solubility and reduces steric hindrance, improving reaction efficiency. The maleimide group reacts selectively with thiol groups (-SH), enabling precise conjugation with cysteine-containing molecules. The succinimidyl ester reacts with primary amines (-NH2), allowing attachment to lysine residues or amine-functionalized compounds. This dual functionality makes it valuable in drug delivery systems, diagnostic assays, and the development of antibody-drug conjugates (ADCs). Its applications also extend to surface modification and the creation of biocompatible materials.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.050 | 10-20 days | $685.85 |
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Maleimide-PEG12-succinimidyl ester
Used primarily in bioconjugation, this chemical serves as a linker to attach biomolecules like proteins, peptides, or antibodies to other entities, such as nanoparticles or surfaces. Its PEG spacer enhances solubility and reduces steric hindrance, improving reaction efficiency. The maleimide group reacts selectively with thiol groups (-SH), enabling precise conjugation with cysteine-containing molecules. The succinimidyl ester reacts with primary amines (-NH2), allowing attachment to lysine residues or amine-functionalized compounds. This dual functionality makes it valuable in drug delivery systems, diagnostic assays, and the development of antibody-drug conjugates (ADCs). Its applications also extend to surface modification and the creation of biocompatible materials.
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