N-(Propargyl-peg4)-n-bis(peg4-acid)
95%
- Product Code: 55174
CAS:
2093153-09-2
| Molecular Weight: | 727.83 g./mol | Molecular Formula: | C₃₃H₆₁NO₁₆ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD30723276 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8°C, sealed, dry |
Product Description:
This chemical is widely used in bioconjugation and drug delivery systems due to its unique structure, which includes PEG (polyethylene glycol) chains and a propargyl group. The PEG chains enhance solubility and biocompatibility, making it suitable for modifying proteins, peptides, and other biomolecules to improve their stability and reduce immunogenicity. The propargyl group allows for efficient click chemistry reactions, particularly with azides, enabling precise and rapid attachment of targeting ligands, drugs, or imaging agents. Its application is prominent in the development of antibody-drug conjugates (ADCs), where it serves as a linker to connect therapeutic payloads to antibodies. Additionally, it is utilized in the synthesis of hydrogels and nanoparticles for controlled drug release and tissue engineering. Its versatility also extends to diagnostic applications, where it aids in the creation of fluorescent or radioactive probes for imaging and detection purposes.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.250 | 10-20 days | ฿50,715.00 |
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N-(Propargyl-peg4)-n-bis(peg4-acid)
This chemical is widely used in bioconjugation and drug delivery systems due to its unique structure, which includes PEG (polyethylene glycol) chains and a propargyl group. The PEG chains enhance solubility and biocompatibility, making it suitable for modifying proteins, peptides, and other biomolecules to improve their stability and reduce immunogenicity. The propargyl group allows for efficient click chemistry reactions, particularly with azides, enabling precise and rapid attachment of targeting ligands, drugs, or imaging agents. Its application is prominent in the development of antibody-drug conjugates (ADCs), where it serves as a linker to connect therapeutic payloads to antibodies. Additionally, it is utilized in the synthesis of hydrogels and nanoparticles for controlled drug release and tissue engineering. Its versatility also extends to diagnostic applications, where it aids in the creation of fluorescent or radioactive probes for imaging and detection purposes.
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