AP1867-2-carboxymethoxy(FKBP12 Ligand)
98%
- Product Code: 55412
CAS:
2230613-03-1
| Molecular Weight: | 693.79 g./mol | Molecular Formula: | C₃₈H₄₇NO₁₁ |
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| Density: | Storage Condition: | -20°C, airtight, dry |
Product Description:
AP1867-2-carboxymethoxy is primarily used in chemical biology and biomedical research as a tool for targeted protein degradation and manipulation. It functions as a ligand for FKBP12, a protein that can be engineered into fusion proteins for precise control over cellular processes. This compound is often utilized in dimerization systems, where it induces the association of two proteins of interest, enabling researchers to study protein-protein interactions, signal transduction pathways, and gene expression regulation. Additionally, it plays a key role in the development of targeted therapies, particularly in the field of PROTACs (Proteolysis Targeting Chimeras), where it helps degrade specific disease-causing proteins by recruiting them to the cellular degradation machinery. Its application extends to studying cellular functions and developing novel therapeutic strategies for diseases such as cancer and neurodegenerative disorders.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.010 | 10-20 days | ฿71,073.00 |
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AP1867-2-carboxymethoxy(FKBP12 Ligand)
AP1867-2-carboxymethoxy is primarily used in chemical biology and biomedical research as a tool for targeted protein degradation and manipulation. It functions as a ligand for FKBP12, a protein that can be engineered into fusion proteins for precise control over cellular processes. This compound is often utilized in dimerization systems, where it induces the association of two proteins of interest, enabling researchers to study protein-protein interactions, signal transduction pathways, and gene expression regulation. Additionally, it plays a key role in the development of targeted therapies, particularly in the field of PROTACs (Proteolysis Targeting Chimeras), where it helps degrade specific disease-causing proteins by recruiting them to the cellular degradation machinery. Its application extends to studying cellular functions and developing novel therapeutic strategies for diseases such as cancer and neurodegenerative disorders.
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