AY 9944

≥98%

  • Product Code: 55455
  CAS:    366-93-8
Molecular Weight: 464.30 g./mol Molecular Formula: C₂₂H₃₀Cl₄N₂
EC Number: MDL Number: MFCD00034973
Melting Point: Boiling Point:
Density: Storage Condition: 2-8°C, dry, sealed
Product Description: AY 9944 is primarily used in biochemical research to study cholesterol biosynthesis. It acts as an inhibitor of the enzyme 7-dehydrocholesterol reductase, which is crucial in the final steps of cholesterol synthesis. By inhibiting this enzyme, AY 9944 is utilized to investigate the effects of cholesterol depletion in cellular and animal models. This has significant implications for understanding diseases related to cholesterol metabolism, such as Smith-Lemli-Opitz syndrome, a genetic disorder characterized by defective cholesterol synthesis. Additionally, AY 9944 is employed in pharmacological studies to explore potential therapeutic interventions targeting cholesterol pathways, aiding in the development of treatments for hypercholesterolemia and related cardiovascular conditions.
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
0.010 10-20 days $566.29
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0.025 10-20 days $1,238.77
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AY 9944
AY 9944 is primarily used in biochemical research to study cholesterol biosynthesis. It acts as an inhibitor of the enzyme 7-dehydrocholesterol reductase, which is crucial in the final steps of cholesterol synthesis. By inhibiting this enzyme, AY 9944 is utilized to investigate the effects of cholesterol depletion in cellular and animal models. This has significant implications for understanding diseases related to cholesterol metabolism, such as Smith-Lemli-Opitz syndrome, a genetic disorder characterized by defective cholesterol synthesis. Additionally, AY 9944 is employed in pharmacological studies to explore potential therapeutic interventions targeting cholesterol pathways, aiding in the development of treatments for hypercholesterolemia and related cardiovascular conditions.
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