Pomalidomide-amino-PEG4-NH2 hydrochloride
≥98%
- Product Code: 55475
CAS:
2331259-45-9
| Molecular Weight: | 542.97 g./mol | Molecular Formula: | C₂₃H₃₁ClN₄O₉ |
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| Density: | Storage Condition: | -20°C, away from light, dry, sealed |
Product Description:
Pomalidomide-amino-PEG4-NH2 hydrochloride is primarily utilized in the development of targeted cancer therapies, particularly in the field of proteolysis-targeting chimeras (PROTACs). Its structure allows it to act as a linker molecule, connecting a target protein-binding ligand (such as pomalidomide) to an E3 ubiquitin ligase-recruiting moiety. This facilitates the degradation of specific disease-causing proteins, offering a promising approach for treating conditions like multiple myeloma and other cancers. Additionally, its PEG4 spacer enhances solubility and stability, making it suitable for use in bioconjugation and drug delivery systems. This compound is also explored in research for its potential in immunotherapy and as a tool for studying protein-protein interactions in cellular pathways.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.025 | 10-20 days | ฿34,200.00 |
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Pomalidomide-amino-PEG4-NH2 hydrochloride
Pomalidomide-amino-PEG4-NH2 hydrochloride is primarily utilized in the development of targeted cancer therapies, particularly in the field of proteolysis-targeting chimeras (PROTACs). Its structure allows it to act as a linker molecule, connecting a target protein-binding ligand (such as pomalidomide) to an E3 ubiquitin ligase-recruiting moiety. This facilitates the degradation of specific disease-causing proteins, offering a promising approach for treating conditions like multiple myeloma and other cancers. Additionally, its PEG4 spacer enhances solubility and stability, making it suitable for use in bioconjugation and drug delivery systems. This compound is also explored in research for its potential in immunotherapy and as a tool for studying protein-protein interactions in cellular pathways.
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