DBCO-PEG1-NH-Boc
97%
- Product Code: 55485
CAS:
2364591-77-3
| Molecular Weight: | 491.58 g./mol | Molecular Formula: | C₂₈H₃₃N₃O₅ |
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| Density: | Storage Condition: | -20°C, sealed, dry |
Product Description:
This compound is widely used in bioconjugation and click chemistry applications due to its unique properties. The DBCO (dibenzocyclooctyne) group enables strain-promoted azide-alkyne cycloaddition reactions, allowing for efficient and selective coupling with azide-containing molecules without the need for a catalyst. This makes it particularly useful in labeling biomolecules, such as proteins, peptides, and antibodies, for research and diagnostic purposes. The PEG (polyethylene glycol) spacer enhances solubility and reduces steric hindrance, improving the efficiency of the conjugation process. The NH-Boc (tert-butyloxycarbonyl-protected amine) group provides a protected amine functionality, which can be deprotected to introduce additional reactive sites for further modifications. This compound is especially valuable in drug delivery systems, where it facilitates the targeted attachment of therapeutic agents to carriers or biomolecules. Additionally, it is employed in the development of bioimaging probes and the study of molecular interactions in biological systems.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.050 | 10-20 days | ฿5,625.00 |
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| 0.250 | 10-20 days | ฿15,300.00 |
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DBCO-PEG1-NH-Boc
This compound is widely used in bioconjugation and click chemistry applications due to its unique properties. The DBCO (dibenzocyclooctyne) group enables strain-promoted azide-alkyne cycloaddition reactions, allowing for efficient and selective coupling with azide-containing molecules without the need for a catalyst. This makes it particularly useful in labeling biomolecules, such as proteins, peptides, and antibodies, for research and diagnostic purposes. The PEG (polyethylene glycol) spacer enhances solubility and reduces steric hindrance, improving the efficiency of the conjugation process. The NH-Boc (tert-butyloxycarbonyl-protected amine) group provides a protected amine functionality, which can be deprotected to introduce additional reactive sites for further modifications. This compound is especially valuable in drug delivery systems, where it facilitates the targeted attachment of therapeutic agents to carriers or biomolecules. Additionally, it is employed in the development of bioimaging probes and the study of molecular interactions in biological systems.
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