PXS-5153A
98%
- Product Code: 56094
CAS:
2125956-82-1
| Molecular Weight: | 475.404 g./mol | Molecular Formula: | C₂₀H₂₅Cl₂FN₄O₂S |
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| Density: | Storage Condition: | -20°C, airtight, dry |
Product Description:
PXS-5153A is primarily investigated for its potential therapeutic applications in treating fibrotic diseases. It functions as a selective inhibitor of lysyl oxidase-like 2 (LOXL2), an enzyme that plays a critical role in the cross-linking of collagen and elastin, processes that contribute to fibrosis. By inhibiting LOXL2, PXS-5153A aims to reduce the excessive deposition of extracellular matrix components, which is a hallmark of fibrotic conditions. This makes it a promising candidate for treating diseases such as liver fibrosis, pulmonary fibrosis, and kidney fibrosis. Preclinical studies have shown that PXS-5153A can effectively attenuate fibrosis progression in animal models, highlighting its potential as a novel anti-fibrotic agent. Further research and clinical trials are ongoing to evaluate its efficacy and safety in humans.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.010 | 10-20 days | ฿58,491.00 |
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PXS-5153A
PXS-5153A is primarily investigated for its potential therapeutic applications in treating fibrotic diseases. It functions as a selective inhibitor of lysyl oxidase-like 2 (LOXL2), an enzyme that plays a critical role in the cross-linking of collagen and elastin, processes that contribute to fibrosis. By inhibiting LOXL2, PXS-5153A aims to reduce the excessive deposition of extracellular matrix components, which is a hallmark of fibrotic conditions. This makes it a promising candidate for treating diseases such as liver fibrosis, pulmonary fibrosis, and kidney fibrosis. Preclinical studies have shown that PXS-5153A can effectively attenuate fibrosis progression in animal models, highlighting its potential as a novel anti-fibrotic agent. Further research and clinical trials are ongoing to evaluate its efficacy and safety in humans.
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