SIS3 HCl

97%

  • Product Code: 57264
  CAS:    521984-48-5
Molecular Weight: 489.99 g./mol Molecular Formula: C₂₈H₂₇N₃O₃HCl
EC Number: MDL Number: MFCD09265258
Melting Point: Boiling Point:
Density: Storage Condition: -20℃
Product Description: SIS3 HCl is primarily used in research settings to study the TGF-β signaling pathway. It acts as a specific inhibitor of Smad3 phosphorylation, making it a valuable tool for investigating the role of Smad3 in cellular processes such as fibrosis, inflammation, and cancer progression. Researchers utilize SIS3 HCl to explore its potential therapeutic effects in diseases where TGF-β signaling is dysregulated, including pulmonary fibrosis, liver fibrosis, and certain types of cancer. Additionally, it is employed in in vitro and in vivo studies to better understand the mechanisms of TGF-β-mediated cellular responses and to develop targeted therapies. Its ability to selectively inhibit Smad3 makes it a key compound in the field of molecular biology and drug discovery.
Product Specification:
Test Specification
APPEARANCE Light yellow to Brown powder to crystal
PURITY 96.5-100
Infrared spectrum Conforms to Structure
NMR Conforms to Structure
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
0.001 10-20 days ฿4,100.00
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-
0.005 10-20 days ฿9,880.00
+
-
0.025 10-20 days ฿17,790.00
+
-
0.050 10-20 days ฿22,800.00
+
-
SIS3 HCl
SIS3 HCl is primarily used in research settings to study the TGF-β signaling pathway. It acts as a specific inhibitor of Smad3 phosphorylation, making it a valuable tool for investigating the role of Smad3 in cellular processes such as fibrosis, inflammation, and cancer progression. Researchers utilize SIS3 HCl to explore its potential therapeutic effects in diseases where TGF-β signaling is dysregulated, including pulmonary fibrosis, liver fibrosis, and certain types of cancer. Additionally, it is employed in in vitro and in vivo studies to better understand the mechanisms of TGF-β-mediated cellular responses and to develop targeted therapies. Its ability to selectively inhibit Smad3 makes it a key compound in the field of molecular biology and drug discovery.
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