5'-tert-Butyldimethylsilyloxy-2'-deoxyguanosine

95%

  • Product Code: 58373
  CAS:    51549-33-8
Molecular Weight: 381.5 g./mol Molecular Formula: C₁₆H₂₇N₅O₄Si
EC Number: MDL Number:
Melting Point: Boiling Point:
Density: Storage Condition: 2-8℃
Product Description: Used primarily in the synthesis of oligonucleotides, this chemical serves as a protecting group for the hydroxyl group in nucleosides. Its application is critical in the field of nucleic acid chemistry, where it helps in the stepwise construction of DNA sequences during solid-phase synthesis. The tert-butyldimethylsilyl (TBDMS) group provides stability to the nucleoside during the chemical reactions, ensuring that the desired sequence is accurately assembled. This compound is particularly valuable in the development of therapeutic oligonucleotides, such as antisense drugs and siRNA, where precise control over the molecular structure is essential for biological activity. Additionally, it is utilized in research settings for the study of DNA repair mechanisms and the synthesis of modified nucleosides with potential antiviral or anticancer properties.
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
0.025 10-20 days ฿4,680.00
+
-
0.100 10-20 days ฿14,400.00
+
-
5'-tert-Butyldimethylsilyloxy-2'-deoxyguanosine
Used primarily in the synthesis of oligonucleotides, this chemical serves as a protecting group for the hydroxyl group in nucleosides. Its application is critical in the field of nucleic acid chemistry, where it helps in the stepwise construction of DNA sequences during solid-phase synthesis. The tert-butyldimethylsilyl (TBDMS) group provides stability to the nucleoside during the chemical reactions, ensuring that the desired sequence is accurately assembled. This compound is particularly valuable in the development of therapeutic oligonucleotides, such as antisense drugs and siRNA, where precise control over the molecular structure is essential for biological activity. Additionally, it is utilized in research settings for the study of DNA repair mechanisms and the synthesis of modified nucleosides with potential antiviral or anticancer properties.
Mechanism -
Appearance -
Longevity -
Strength -
Storage -
Shelf Life -
Allergen(s) -
Dosage (Range) -
Dosage (Per Day) -
Mix Method -
Heat Resistance -
Stable in pH range -
Solubility -
Product Types -
INCI -

Cart

No products

Subtotal: ฿0.00
฿0.00 Total :