5'-O-Trt-dI

97%

  • Product Code: 58374
  CAS:    911430-74-5
Molecular Weight: 494.54 g./mol Molecular Formula: C₂₉H₂₆N₄O₄
EC Number: MDL Number:
Melting Point: Boiling Point: 755.8±70.0 °C(Predicted)
Density: 1.35±0.1 g/cm3(Predicted) Storage Condition: 2-8℃
Product Description: Used in the synthesis of oligonucleotides, particularly in solid-phase synthesis where it serves as a protecting group for the 5'-hydroxyl group of nucleosides. This protection is crucial during the stepwise assembly of DNA or RNA sequences, ensuring the correct addition of nucleotides without unwanted side reactions. After the synthesis, the trityl group can be selectively removed under mild acidic conditions, allowing for the continuation of the sequence assembly or the final deprotection of the oligonucleotide. Its application is essential in the production of primers, probes, and other nucleic acid-based tools used in molecular biology, diagnostics, and therapeutic research.
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
0.025 10-20 days Ft50,422.83
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-
0.100 10-20 days Ft155,147.16
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-
5'-O-Trt-dI
Used in the synthesis of oligonucleotides, particularly in solid-phase synthesis where it serves as a protecting group for the 5'-hydroxyl group of nucleosides. This protection is crucial during the stepwise assembly of DNA or RNA sequences, ensuring the correct addition of nucleotides without unwanted side reactions. After the synthesis, the trityl group can be selectively removed under mild acidic conditions, allowing for the continuation of the sequence assembly or the final deprotection of the oligonucleotide. Its application is essential in the production of primers, probes, and other nucleic acid-based tools used in molecular biology, diagnostics, and therapeutic research.
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