NHS-PEG4-SPDP
98%
- Product Code: 58949
CAS:
1334177-95-5
| Molecular Weight: | 559.65 g./mol | Molecular Formula: | C₂₃H₃₃N₃O₉S₂ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD13185001 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20°C |
Product Description:
Used extensively in bioconjugation and crosslinking applications, it facilitates the attachment of biomolecules such as proteins, peptides, and antibodies to other entities like nanoparticles or surfaces. The NHS ester group reacts efficiently with primary amines, forming stable amide bonds, while the SPDP group enables thiol-reactive conjugation, allowing for the formation of disulfide bonds. This dual functionality makes it a versatile tool in drug delivery systems, where it can be used to create targeted therapeutic conjugates. Additionally, it is employed in the development of diagnostic assays, enabling the labeling of biomolecules for detection and analysis. Its PEG spacer enhances solubility and reduces steric hindrance, improving the efficiency of conjugation reactions.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.010 | 10-20 days | ฿6,670.00 |
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| 0.100 | 10-20 days | ฿58,600.00 |
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NHS-PEG4-SPDP
Used extensively in bioconjugation and crosslinking applications, it facilitates the attachment of biomolecules such as proteins, peptides, and antibodies to other entities like nanoparticles or surfaces. The NHS ester group reacts efficiently with primary amines, forming stable amide bonds, while the SPDP group enables thiol-reactive conjugation, allowing for the formation of disulfide bonds. This dual functionality makes it a versatile tool in drug delivery systems, where it can be used to create targeted therapeutic conjugates. Additionally, it is employed in the development of diagnostic assays, enabling the labeling of biomolecules for detection and analysis. Its PEG spacer enhances solubility and reduces steric hindrance, improving the efficiency of conjugation reactions.
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