trans-4-(tert-Butyldiphenylsilyloxy)-L-proline
≥98%
- Product Code: 62466
CAS:
259212-61-8
| Molecular Weight: | 369.54 g./mol | Molecular Formula: | C₂₁H₂₇NO₃Si |
|---|---|---|---|
| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | room temperature, dry |
Product Description:
This compound is primarily utilized in organic synthesis, particularly in peptide chemistry, where it serves as a protecting group for the hydroxyl and carboxyl functionalities of proline. Its tert-butyldiphenylsilyl (TBDPS) group is highly effective in shielding the hydroxyl group during complex synthetic reactions, ensuring selective transformations elsewhere in the molecule. Additionally, it is employed in the synthesis of modified peptides and peptidomimetics, where the steric bulk of the TBDPS group helps control stereochemistry and prevent unwanted side reactions. Its stability under various reaction conditions makes it a valuable tool in the development of pharmaceuticals and bioactive compounds.
Product Specification:
| Test | Specification |
|---|---|
| APPEARANCE | White to Almost white powder to crystal |
| PURITY | 97.5-100 |
| Infrared spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.200 | 10-20 days | ฿3,600.00 |
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| 1.000 | 10-20 days | ฿17,020.00 |
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trans-4-(tert-Butyldiphenylsilyloxy)-L-proline
This compound is primarily utilized in organic synthesis, particularly in peptide chemistry, where it serves as a protecting group for the hydroxyl and carboxyl functionalities of proline. Its tert-butyldiphenylsilyl (TBDPS) group is highly effective in shielding the hydroxyl group during complex synthetic reactions, ensuring selective transformations elsewhere in the molecule. Additionally, it is employed in the synthesis of modified peptides and peptidomimetics, where the steric bulk of the TBDPS group helps control stereochemistry and prevent unwanted side reactions. Its stability under various reaction conditions makes it a valuable tool in the development of pharmaceuticals and bioactive compounds.
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