GSK2606414

≥98%

  • Product Code: 62923
  CAS:    1337531-36-8
Molecular Weight: 451.44 g./mol Molecular Formula: C₂₄H₂₀F₃N₅O
EC Number: MDL Number:
Melting Point: Boiling Point:
Density: Storage Condition: -20°C
Product Description: GSK2606414 is primarily used in research settings to study the unfolded protein response (UPR) pathway. It acts as a potent inhibitor of the PERK (PKR-like ER kinase) enzyme, which plays a critical role in managing cellular stress caused by the accumulation of misfolded proteins in the endoplasmic reticulum. By inhibiting PERK, this compound helps researchers understand the mechanisms of cellular stress responses and their implications in diseases such as cancer, neurodegenerative disorders, and diabetes. Its application is particularly valuable in preclinical studies aimed at exploring therapeutic strategies targeting the UPR pathway.
Product Specification:
Test Specification
APPEARANCE White to off-white solid
PURITY 97.5-100
Infrared spectrum Conforms to Structure
NMR Conforms to Structure
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
0.005 10-20 days ฿8,710.00
+
-
0.025 10-20 days ฿23,990.00
+
-
GSK2606414
GSK2606414 is primarily used in research settings to study the unfolded protein response (UPR) pathway. It acts as a potent inhibitor of the PERK (PKR-like ER kinase) enzyme, which plays a critical role in managing cellular stress caused by the accumulation of misfolded proteins in the endoplasmic reticulum. By inhibiting PERK, this compound helps researchers understand the mechanisms of cellular stress responses and their implications in diseases such as cancer, neurodegenerative disorders, and diabetes. Its application is particularly valuable in preclinical studies aimed at exploring therapeutic strategies targeting the UPR pathway.
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