LY-335979
≥98%
- Product Code: 64098
Alias:
Related CAS number: 167465-36-3
CAS:
167354-41-8
| Molecular Weight: | 527.6 g./mol | Molecular Formula: | C₃₂H₃₁F₂N₃O₂ |
|---|---|---|---|
| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20℃ |
Product Description:
LY-335979 is primarily utilized in research settings to study the mechanisms of multidrug resistance in cancer cells. It functions as a potent inhibitor of P-glycoprotein, a protein that often leads to resistance against various chemotherapeutic agents by pumping drugs out of cancer cells. By blocking this protein, LY-335979 helps enhance the effectiveness of chemotherapy drugs, allowing them to remain inside the cancer cells and exert their cytotoxic effects. This makes it a valuable tool in preclinical studies aimed at developing strategies to overcome drug resistance in cancer treatment. Additionally, it is used in pharmacological experiments to understand the role of P-glycoprotein in drug transport and absorption, contributing to the development of more efficient therapeutic approaches.
Product Specification:
| Test | Specification |
|---|---|
| APPEARANCE | Light yellow to yellow Powder |
| PURITY | 97.5-100 |
| Infrared spectrum | Conforms to Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.001 | 10-20 days | ฿4,390.00 |
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| 0.005 | 10-20 days | ฿15,580.00 |
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LY-335979
LY-335979 is primarily utilized in research settings to study the mechanisms of multidrug resistance in cancer cells. It functions as a potent inhibitor of P-glycoprotein, a protein that often leads to resistance against various chemotherapeutic agents by pumping drugs out of cancer cells. By blocking this protein, LY-335979 helps enhance the effectiveness of chemotherapy drugs, allowing them to remain inside the cancer cells and exert their cytotoxic effects. This makes it a valuable tool in preclinical studies aimed at developing strategies to overcome drug resistance in cancer treatment. Additionally, it is used in pharmacological experiments to understand the role of P-glycoprotein in drug transport and absorption, contributing to the development of more efficient therapeutic approaches.
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