2,5-Dioxopyrrolidin-1-yl 6-(3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamido)hexanoate
97%
- Product Code: 64503
CAS:
367927-39-7
| Molecular Weight: | 379.36 g./mol | Molecular Formula: | C₁₇H₂₁N₃O₇ |
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| EC Number: | MDL Number: | MFCD01863460 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20°C, store under inert gas |
Product Description:
This compound is widely used in bioconjugation and protein labeling applications due to its reactive ester and maleimide functional groups. The NHS ester moiety reacts efficiently with primary amines, enabling covalent attachment to proteins, peptides, or other amine-containing molecules. Simultaneously, the maleimide group allows for selective conjugation with thiol groups, such as those found in cysteine residues. This dual functionality makes it a valuable tool for creating stable crosslinks between biomolecules, particularly in antibody-drug conjugates (ADCs), enzyme immobilization, and the development of diagnostic assays. Its application is also prominent in the preparation of polymer-drug conjugates, where it facilitates the controlled release of therapeutic agents. Additionally, it is utilized in surface modification techniques to functionalize materials for biomedical and biotechnological purposes.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.050 | 10-20 days | ฿13,140.00 |
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| 0.250 | 10-20 days | ฿45,801.00 |
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2,5-Dioxopyrrolidin-1-yl 6-(3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamido)hexanoate
This compound is widely used in bioconjugation and protein labeling applications due to its reactive ester and maleimide functional groups. The NHS ester moiety reacts efficiently with primary amines, enabling covalent attachment to proteins, peptides, or other amine-containing molecules. Simultaneously, the maleimide group allows for selective conjugation with thiol groups, such as those found in cysteine residues. This dual functionality makes it a valuable tool for creating stable crosslinks between biomolecules, particularly in antibody-drug conjugates (ADCs), enzyme immobilization, and the development of diagnostic assays. Its application is also prominent in the preparation of polymer-drug conjugates, where it facilitates the controlled release of therapeutic agents. Additionally, it is utilized in surface modification techniques to functionalize materials for biomedical and biotechnological purposes.
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