5'-O-DMT-2'-O-tert-Butyldimethylsilyl-N6-methyl-adenosine 3'-CE phosphoramidite
98%
- Product Code: 64964
CAS:
588698-79-7
| Molecular Weight: | 898.11 g./mol | Molecular Formula: | C₄₇H₆₄N₇O₇PSi |
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| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | 859.0±75.0 °C(Predicted) | |
| Density: | Storage Condition: | 2-8℃ |
Product Description:
This chemical is widely used in the synthesis of oligonucleotides, particularly in the field of nucleic acid research and drug development. It serves as a key building block in solid-phase oligonucleotide synthesis, where it is incorporated into RNA sequences to study gene expression, RNA interference, and other molecular biology processes. Its protective groups, such as DMT and TBDMS, ensure selective reactivity during the synthesis, enabling precise control over the assembly of RNA strands. Additionally, it is employed in the development of therapeutic oligonucleotides, including antisense RNA and siRNA, which are used to target and regulate specific genes in diseases like cancer and genetic disorders. Its stability and compatibility with automated synthesizers make it a valuable tool in both academic and industrial settings.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.025 | 10-20 days | $75.07 |
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| 0.100 | 10-20 days | $232.22 |
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5'-O-DMT-2'-O-tert-Butyldimethylsilyl-N6-methyl-adenosine 3'-CE phosphoramidite
This chemical is widely used in the synthesis of oligonucleotides, particularly in the field of nucleic acid research and drug development. It serves as a key building block in solid-phase oligonucleotide synthesis, where it is incorporated into RNA sequences to study gene expression, RNA interference, and other molecular biology processes. Its protective groups, such as DMT and TBDMS, ensure selective reactivity during the synthesis, enabling precise control over the assembly of RNA strands. Additionally, it is employed in the development of therapeutic oligonucleotides, including antisense RNA and siRNA, which are used to target and regulate specific genes in diseases like cancer and genetic disorders. Its stability and compatibility with automated synthesizers make it a valuable tool in both academic and industrial settings.
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