[S(R)]-N-[(1S)-1-[2-(Di-tert-butylphosphanyl)phenyl]phenylmethyl]-2-methyl-2-propanesulfinamide

≥95%

  • Product Code: 65018
  CAS:    2565792-23-4
Molecular Weight: 431.62 g./mol Molecular Formula: C₂₅H₃₈NOPS
EC Number: MDL Number: MFCD32697225
Melting Point: Boiling Point:
Density: Storage Condition: room temperature, inert gas
Product Description: This chemical is primarily utilized as a chiral ligand in asymmetric catalysis, particularly in transition metal-catalyzed reactions. Its application is significant in the synthesis of enantiomerically pure compounds, which are crucial in the pharmaceutical industry for the production of active pharmaceutical ingredients (APIs). The compound’s structure, featuring a di-tert-butylphosphanyl group and a sulfinamide moiety, allows it to effectively coordinate with metals like palladium, rhodium, or iridium, enhancing the selectivity and efficiency of catalytic processes such as hydrogenation, cross-coupling, and allylic substitution reactions. Its use is pivotal in creating complex molecules with high enantiomeric purity, which is essential for developing drugs with specific biological activities and reduced side effects. Additionally, it finds application in academic research for exploring new catalytic methodologies and optimizing synthetic routes for complex organic molecules.
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
0.005 10-20 days $105.25
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0.025 10-20 days $405.35
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0.100 10-20 days $1,267.61
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[S(R)]-N-[(1S)-1-[2-(Di-tert-butylphosphanyl)phenyl]phenylmethyl]-2-methyl-2-propanesulfinamide
This chemical is primarily utilized as a chiral ligand in asymmetric catalysis, particularly in transition metal-catalyzed reactions. Its application is significant in the synthesis of enantiomerically pure compounds, which are crucial in the pharmaceutical industry for the production of active pharmaceutical ingredients (APIs). The compound’s structure, featuring a di-tert-butylphosphanyl group and a sulfinamide moiety, allows it to effectively coordinate with metals like palladium, rhodium, or iridium, enhancing the selectivity and efficiency of catalytic processes such as hydrogenation, cross-coupling, and allylic substitution reactions. Its use is pivotal in creating complex molecules with high enantiomeric purity, which is essential for developing drugs with specific biological activities and reduced side effects. Additionally, it finds application in academic research for exploring new catalytic methodologies and optimizing synthetic routes for complex organic molecules.
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