Guandine thiocyanate

≥98%

  • Product Code: 65425
  Alias:    Guanidine isothiocyanate; Guanidine thiocyanate
  CAS:    593-84-0
Molecular Weight: 118.16 g./mol Molecular Formula: C₂H₆N₄S
EC Number: 209-812-1 MDL Number: MFCD00013027
Melting Point: 120-122 °C(lit.) Boiling Point:
Density: 1.103 g/mL at 20 °C Storage Condition: room temperature
Product Description: Guanidine thiocyanate is widely used in molecular biology for the isolation of nucleic acids, particularly RNA, due to its ability to denature proteins and inhibit RNases. It is a key component in many RNA extraction protocols, including the popular single-step method using phenol-chloroform. The chemical works by disrupting cell membranes and denaturing proteins, allowing RNA to be separated and purified. It is also employed in DNA extraction, though less commonly. Additionally, guanidine thiocyanate is utilized in the preparation of samples for downstream applications like PCR, sequencing, and hybridization. Its strong chaotropic properties make it effective in solubilizing biological materials, ensuring high-quality nucleic acid yields.
Product Specification:
Test Specification
APPEARANCE Colorless to White to Almost white powder to crystal
PURITY 98-100
MELTING POINT 115-121
Infrared spectrum Conforms to Structure
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
25.000 10-20 days ฿460.00
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100.000 10-20 days ฿590.00
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500.000 10-20 days ฿2,890.00
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2500.000 10-20 days ฿13,300.00
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10000.000 10-20 days ฿49,200.00
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25000.000 10-20 days ฿94,200.00
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Guandine thiocyanate
Guanidine thiocyanate is widely used in molecular biology for the isolation of nucleic acids, particularly RNA, due to its ability to denature proteins and inhibit RNases. It is a key component in many RNA extraction protocols, including the popular single-step method using phenol-chloroform. The chemical works by disrupting cell membranes and denaturing proteins, allowing RNA to be separated and purified. It is also employed in DNA extraction, though less commonly. Additionally, guanidine thiocyanate is utilized in the preparation of samples for downstream applications like PCR, sequencing, and hybridization. Its strong chaotropic properties make it effective in solubilizing biological materials, ensuring high-quality nucleic acid yields.
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