Guandine thiocyanate
≥98%
- Product Code: 65425
Alias:
Guanidine isothiocyanate; Guanidine thiocyanate
CAS:
593-84-0
Molecular Weight: | 118.16 g./mol | Molecular Formula: | C₂H₆N₄S |
---|---|---|---|
EC Number: | 209-812-1 | MDL Number: | MFCD00013027 |
Melting Point: | 120-122 °C(lit.) | Boiling Point: | |
Density: | 1.103 g/mL at 20 °C | Storage Condition: | room temperature |
Product Description:
Guanidine thiocyanate is widely used in molecular biology for the isolation of nucleic acids, particularly RNA, due to its ability to denature proteins and inhibit RNases. It is a key component in many RNA extraction protocols, including the popular single-step method using phenol-chloroform. The chemical works by disrupting cell membranes and denaturing proteins, allowing RNA to be separated and purified. It is also employed in DNA extraction, though less commonly. Additionally, guanidine thiocyanate is utilized in the preparation of samples for downstream applications like PCR, sequencing, and hybridization. Its strong chaotropic properties make it effective in solubilizing biological materials, ensuring high-quality nucleic acid yields.
Product Specification:
Test | Specification |
---|---|
APPEARANCE | Colorless to White to Almost white powder to crystal |
PURITY | 98-100 |
MELTING POINT | 115-121 |
Infrared spectrum | Conforms to Structure |
Sizes / Availability / Pricing:
Size (g) | Availability | Price | Quantity |
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25.000 | 10-20 days | ฿460.00 |
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100.000 | 10-20 days | ฿590.00 |
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500.000 | 10-20 days | ฿2,890.00 |
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2500.000 | 10-20 days | ฿13,300.00 |
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10000.000 | 10-20 days | ฿49,200.00 |
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25000.000 | 10-20 days | ฿94,200.00 |
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Guandine thiocyanate
Guanidine thiocyanate is widely used in molecular biology for the isolation of nucleic acids, particularly RNA, due to its ability to denature proteins and inhibit RNases. It is a key component in many RNA extraction protocols, including the popular single-step method using phenol-chloroform. The chemical works by disrupting cell membranes and denaturing proteins, allowing RNA to be separated and purified. It is also employed in DNA extraction, though less commonly. Additionally, guanidine thiocyanate is utilized in the preparation of samples for downstream applications like PCR, sequencing, and hybridization. Its strong chaotropic properties make it effective in solubilizing biological materials, ensuring high-quality nucleic acid yields.
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