JNJ-26854165
>98%
- Product Code: 67652
CAS:
881202-45-5
| Molecular Weight: | 328.41 g./mol | Molecular Formula: | C₂₁H₂₀N₄ |
|---|---|---|---|
| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20℃ |
Product Description:
JNJ-26854165 is primarily investigated for its potential in cancer therapy. It functions as an inhibitor of p53-HDM2 interaction, which is crucial in regulating tumor suppression. By disrupting this interaction, it promotes the activation of p53, a protein that plays a significant role in preventing cancer cell proliferation. This mechanism makes it a promising candidate for treating various cancers, particularly those with wild-type p53. Research is ongoing to explore its efficacy in combination with other anticancer agents, aiming to enhance therapeutic outcomes and overcome drug resistance. Its application is focused on developing targeted treatments for malignancies where p53 pathways are intact but suppressed.
Product Specification:
| Test | Specification |
|---|---|
| APPEARANCE | brown solid |
| PURITY | 98-100 |
| NMR | Conforms to Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.010 | 10-20 days | ฿6,600.00 |
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| 0.050 | 10-20 days | ฿26,000.00 |
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| 0.100 | 10-20 days | ฿48,600.00 |
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JNJ-26854165
JNJ-26854165 is primarily investigated for its potential in cancer therapy. It functions as an inhibitor of p53-HDM2 interaction, which is crucial in regulating tumor suppression. By disrupting this interaction, it promotes the activation of p53, a protein that plays a significant role in preventing cancer cell proliferation. This mechanism makes it a promising candidate for treating various cancers, particularly those with wild-type p53. Research is ongoing to explore its efficacy in combination with other anticancer agents, aiming to enhance therapeutic outcomes and overcome drug resistance. Its application is focused on developing targeted treatments for malignancies where p53 pathways are intact but suppressed.
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| Heat Resistance | - |
| Stable in pH range | - |
| Solubility | - |
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| INCI | - |
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