(R)-(1,2',3,3'-Tetrahydro-1,2'-spirobi[indene]-4,7'-diyl)bis(di-p-tolylphosphine)
98%
- Product Code: 70393
CAS:
528521-87-1
| Molecular Weight: | 644.76 g./mol | Molecular Formula: | C₄₅H₄₂P₂ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD08459345 | |
| Melting Point: | 150-152 °C | Boiling Point: | 722 °C at 760 mmHg |
| Density: | Storage Condition: | 2-8°C |
Product Description:
This chemical is primarily utilized as a chiral ligand in asymmetric catalysis, particularly in transition metal-catalyzed reactions. Its application is significant in the synthesis of enantiomerically pure compounds, which are crucial in the pharmaceutical industry for producing drugs with high stereoselectivity. The compound’s unique spirobiindene structure and di-p-tolylphosphine groups enhance its ability to induce chirality in various organic transformations, such as hydrogenation, cross-coupling, and allylic substitution reactions. Its effectiveness in creating chiral centers makes it valuable for developing active pharmaceutical ingredients (APIs) and fine chemicals with specific stereochemical requirements.
Product Specification:
| Test | Specification |
|---|---|
| APPEARANCE | White Solid |
| PURITY | 97.5-100 |
| Infrared spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.010 | 10-20 days | $235.17 |
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| 0.050 | 10-20 days | $903.71 |
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(R)-(1,2',3,3'-Tetrahydro-1,2'-spirobi[indene]-4,7'-diyl)bis(di-p-tolylphosphine)
This chemical is primarily utilized as a chiral ligand in asymmetric catalysis, particularly in transition metal-catalyzed reactions. Its application is significant in the synthesis of enantiomerically pure compounds, which are crucial in the pharmaceutical industry for producing drugs with high stereoselectivity. The compound’s unique spirobiindene structure and di-p-tolylphosphine groups enhance its ability to induce chirality in various organic transformations, such as hydrogenation, cross-coupling, and allylic substitution reactions. Its effectiveness in creating chiral centers makes it valuable for developing active pharmaceutical ingredients (APIs) and fine chemicals with specific stereochemical requirements.
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