(S)-2-[(Diphenylphosphino)methyl]pyrrolidine

98%

  • Product Code: 70436
  CAS:    60261-46-3
Molecular Weight: 269.321161 g./mol Molecular Formula: C₁₇H₂₀NP
EC Number: MDL Number: MFCD16621443
Melting Point: Boiling Point: 387.1±15.0 °C
Density: 1.043 g/mL at 25 °C Storage Condition: 2-8°C, away from light
Product Description: (S)-2-[(Diphenylphosphino)methyl]pyrrolidine is widely used as a chiral ligand in asymmetric catalysis, particularly in transition metal-catalyzed reactions. It plays a crucial role in enantioselective hydrogenation, where it helps produce chiral molecules with high optical purity, essential in the synthesis of pharmaceuticals and fine chemicals. This ligand is also employed in asymmetric allylic alkylation and cross-coupling reactions, enabling the formation of carbon-carbon and carbon-heteroatom bonds with high stereocontrol. Its application extends to the development of chiral catalysts for organic transformations, contributing to the efficient and selective synthesis of complex molecules in medicinal chemistry and materials science.
Product Specification:
Test Specification
APPEARANCE Colorless to light yellow Liquid
PURITY 97.5-100
Infrared spectrum Conforms to Structure
NMR Conforms to Structure
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
0.050 10-20 days ฿4,820.00
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0.250 10-20 days ฿13,890.00
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(S)-2-[(Diphenylphosphino)methyl]pyrrolidine
(S)-2-[(Diphenylphosphino)methyl]pyrrolidine is widely used as a chiral ligand in asymmetric catalysis, particularly in transition metal-catalyzed reactions. It plays a crucial role in enantioselective hydrogenation, where it helps produce chiral molecules with high optical purity, essential in the synthesis of pharmaceuticals and fine chemicals. This ligand is also employed in asymmetric allylic alkylation and cross-coupling reactions, enabling the formation of carbon-carbon and carbon-heteroatom bonds with high stereocontrol. Its application extends to the development of chiral catalysts for organic transformations, contributing to the efficient and selective synthesis of complex molecules in medicinal chemistry and materials science.
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