(S)-1-(RP)-2-[Bis(4-methoxy-3,5-dimethylphenyl)phosphino]ferrocenylethyldicyclohexylphosphine
97%
- Product Code: 70457
CAS:
166172-66-3
| Molecular Weight: | 710.69 g./mol | Molecular Formula: | C₄₂H₅₆FeO₂P₂ |
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| EC Number: | MDL Number: | MFCD08561152 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2~8℃, inert gas atmosphere |
Product Description:
This chemical is primarily utilized as a chiral ligand in asymmetric catalysis, particularly in transition metal-catalyzed reactions. Its application is significant in the synthesis of enantiomerically pure compounds, which are crucial in the pharmaceutical industry for producing active pharmaceutical ingredients (APIs) with high stereoselectivity. It is often employed in asymmetric hydrogenation, a process that reduces prochiral alkenes, ketones, or imines to chiral products with high enantiomeric excess. This ligand’s unique structure, combining ferrocene and phosphine groups, enhances its ability to induce chirality, making it valuable for creating complex molecules with specific stereochemistry. Additionally, it is used in cross-coupling reactions, such as Suzuki-Miyaura and Heck reactions, to construct carbon-carbon bonds in a stereocontrolled manner. Its robust performance in these transformations makes it a key tool in organic synthesis for developing fine chemicals and agrochemicals.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.050 | 10-20 days | ฿3,888.00 |
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| 0.100 | 10-20 days | ฿6,633.00 |
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| 0.250 | 10-20 days | ฿14,967.00 |
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(S)-1-(RP)-2-[Bis(4-methoxy-3,5-dimethylphenyl)phosphino]ferrocenylethyldicyclohexylphosphine
This chemical is primarily utilized as a chiral ligand in asymmetric catalysis, particularly in transition metal-catalyzed reactions. Its application is significant in the synthesis of enantiomerically pure compounds, which are crucial in the pharmaceutical industry for producing active pharmaceutical ingredients (APIs) with high stereoselectivity. It is often employed in asymmetric hydrogenation, a process that reduces prochiral alkenes, ketones, or imines to chiral products with high enantiomeric excess. This ligand’s unique structure, combining ferrocene and phosphine groups, enhances its ability to induce chirality, making it valuable for creating complex molecules with specific stereochemistry. Additionally, it is used in cross-coupling reactions, such as Suzuki-Miyaura and Heck reactions, to construct carbon-carbon bonds in a stereocontrolled manner. Its robust performance in these transformations makes it a key tool in organic synthesis for developing fine chemicals and agrochemicals.
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