Boc-D-Arg(Pbf)-OH
≥95%
- Product Code: 71227
CAS:
186698-61-3
| Molecular Weight: | 526.65 g./mol | Molecular Formula: | C₂₄H₃₈N₄O₇S |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD00236822 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | -20°C, dry sealed |
Product Description:
This chemical is widely used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS) methods. It serves as a protected form of D-arginine, where the Boc (tert-butyloxycarbonyl) group protects the amino group, and the Pbf (2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl) group protects the guanidine side chain. This protection is crucial to prevent unwanted side reactions during the peptide assembly process. The compound is especially valuable in the synthesis of complex peptides and proteins, where precise control over the sequence and structure is required. It is commonly employed in pharmaceutical research and development, particularly in the creation of peptide-based drugs, hormones, and bioactive peptides. Additionally, it finds use in biochemical studies to investigate protein-protein interactions and enzyme mechanisms. The protection groups can be selectively removed under specific conditions, allowing for the stepwise construction of peptides with high purity and yield.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.250 | 10-20 days | ฿648.00 |
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Boc-D-Arg(Pbf)-OH
This chemical is widely used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS) methods. It serves as a protected form of D-arginine, where the Boc (tert-butyloxycarbonyl) group protects the amino group, and the Pbf (2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl) group protects the guanidine side chain. This protection is crucial to prevent unwanted side reactions during the peptide assembly process. The compound is especially valuable in the synthesis of complex peptides and proteins, where precise control over the sequence and structure is required. It is commonly employed in pharmaceutical research and development, particularly in the creation of peptide-based drugs, hormones, and bioactive peptides. Additionally, it finds use in biochemical studies to investigate protein-protein interactions and enzyme mechanisms. The protection groups can be selectively removed under specific conditions, allowing for the stepwise construction of peptides with high purity and yield.
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