N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine
98%
- Product Code: 72731
CAS:
162012-67-1
| Molecular Weight: | 336.69 g./mol | Molecular Formula: | C₁₄H₇ClF₂N₄O₂ |
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| EC Number: | MDL Number: | ||
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | Room temperature, sealed, dry |
Product Description:
This compound is primarily utilized in the field of medicinal chemistry as a key intermediate in the synthesis of targeted cancer therapies. It serves as a building block for the development of quinazoline-based inhibitors, which are designed to selectively target and inhibit specific tyrosine kinases involved in cancer cell proliferation and survival. Its structure is particularly valuable in creating molecules that can effectively bind to the ATP-binding sites of these kinases, thereby blocking their activity. This makes it a crucial component in the research and production of drugs aimed at treating various cancers, including lung, breast, and colorectal cancers. Additionally, its nitro and fluoro substituents enhance its ability to interact with biological targets, improving the efficacy of the resulting therapeutic agents.
Product Specification:
| Test | Specification |
|---|---|
| APPEARANCE | WHITE TO BROWN SOLID |
| PURITY | 97.5 |
| INFRARED SPECTRUM | Conforms to Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 1.000 | 10-20 days | $18.30 |
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| 5.000 | 10-20 days | $53.71 |
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| 25.000 | 10-20 days | $130.81 |
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| 100.000 | 10-20 days | $455.15 |
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N-(3-Chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine
This compound is primarily utilized in the field of medicinal chemistry as a key intermediate in the synthesis of targeted cancer therapies. It serves as a building block for the development of quinazoline-based inhibitors, which are designed to selectively target and inhibit specific tyrosine kinases involved in cancer cell proliferation and survival. Its structure is particularly valuable in creating molecules that can effectively bind to the ATP-binding sites of these kinases, thereby blocking their activity. This makes it a crucial component in the research and production of drugs aimed at treating various cancers, including lung, breast, and colorectal cancers. Additionally, its nitro and fluoro substituents enhance its ability to interact with biological targets, improving the efficacy of the resulting therapeutic agents.
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