Hexamethylphosphoramide (HMPA)

98%

  • Product Code: 72968
  Alias:    Rokko tsubo sansatsu ;Rokko tsubosatsu sansatsu
  CAS:    680-31-9
Molecular Weight: 179.2 g./mol Molecular Formula: C₆H₁₈N₃PO
EC Number: 211-653-8 MDL Number: MFCD00008303
Melting Point: 7 °C(lit.) Boiling Point: 230-232 °C/740 mm Hg(lit.)
Density: 1.03 g/mL at 25 °C(lit.) Storage Condition: room temperature
Product Description: Hexamethylphosphoramide (HMPA) is primarily used as a polar aprotic solvent in organic synthesis. It is particularly effective in reactions involving strong bases, such as deprotonation and alkylation processes, due to its ability to stabilize anions. HMPA is often employed in the synthesis of complex organic molecules, including pharmaceuticals, where it enhances reaction rates and selectivity. Additionally, it is utilized in polymer chemistry as a solvent for polymerization reactions and in the production of high-performance materials. In some cases, HMPA is also used as a stabilizer or additive in electrochemical applications. However, its use is limited due to toxicity concerns, requiring careful handling and disposal.
Product Specification:
Test Specification
PH VALUE 6.1-8
PurityGC 98 100%
REFRACTIVE INDEX N20D 1.456-1.46
SPECIFIC GRAVITY 2020C 1.025-1.03
WATER BY KARL FISCHER 0-0.1
APPEARANCE Colorless to light yellow liquid
INFRARED SPECTRUM Conforms to Structure
NOTE: This product is low melting point solid,may change state in different environments (solid, liquid or semi-solid)
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
25.000 10-20 days $16.57
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100.000 10-20 days $33.15
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500.000 10-20 days $114.52
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2500.000 10-20 days $563.54
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Hexamethylphosphoramide (HMPA)
Hexamethylphosphoramide (HMPA) is primarily used as a polar aprotic solvent in organic synthesis. It is particularly effective in reactions involving strong bases, such as deprotonation and alkylation processes, due to its ability to stabilize anions. HMPA is often employed in the synthesis of complex organic molecules, including pharmaceuticals, where it enhances reaction rates and selectivity. Additionally, it is utilized in polymer chemistry as a solvent for polymerization reactions and in the production of high-performance materials. In some cases, HMPA is also used as a stabilizer or additive in electrochemical applications. However, its use is limited due to toxicity concerns, requiring careful handling and disposal.
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