N-Boc-cis-4-Fluoro-L-proline Methyl Ester
≥97%
- Product Code: 76510
CAS:
203866-16-4
| Molecular Weight: | 247.26 g./mol | Molecular Formula: | C₁₁H₁₈FNO₄ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD11054130 | |
| Melting Point: | Boiling Point: | ||
| Density: | 1.153(lit.) | Storage Condition: | room temperature, dry |
Product Description:
This compound is primarily utilized in the synthesis of peptides and pharmaceuticals, particularly where the introduction of a fluorine atom is necessary for enhancing biological activity or stability. It serves as a protected form of proline, allowing for selective reactions in peptide coupling processes. The Boc group provides temporary protection for the amine functionality, enabling controlled deprotection during multi-step synthesis. Its application is significant in the development of drug candidates, especially in the field of medicinal chemistry, where fluorinated amino acids are often incorporated to improve metabolic stability and binding affinity. Additionally, it is used in research to study the effects of fluorination on peptide structure and function.
Product Specification:
| Test | Specification |
|---|---|
| APPEARANCE | White to off-white Solid |
| PURITY | 96.5-100 |
| Infrared spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.250 | 10-20 days | $44.40 |
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| 1.000 | 10-20 days | $113.41 |
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| 5.000 | 10-20 days | $306.33 |
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N-Boc-cis-4-Fluoro-L-proline Methyl Ester
This compound is primarily utilized in the synthesis of peptides and pharmaceuticals, particularly where the introduction of a fluorine atom is necessary for enhancing biological activity or stability. It serves as a protected form of proline, allowing for selective reactions in peptide coupling processes. The Boc group provides temporary protection for the amine functionality, enabling controlled deprotection during multi-step synthesis. Its application is significant in the development of drug candidates, especially in the field of medicinal chemistry, where fluorinated amino acids are often incorporated to improve metabolic stability and binding affinity. Additionally, it is used in research to study the effects of fluorination on peptide structure and function.
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