Fmoc-D-Arg(Pbf)-OH
98%
- Product Code: 76582
CAS:
187618-60-0
Molecular Weight: | 648.8 g./mol | Molecular Formula: | C₃₄H₄₀N₄O₇S |
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Density: | Storage Condition: | 2-8°C, sealed, dry |
Product Description:
This chemical is widely used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS) methods. It serves as a building block for introducing D-arginine residues into peptide sequences. The Fmoc (fluorenylmethyloxycarbonyl) group acts as a protecting group for the amino group, ensuring selective reactions during peptide chain assembly. The Pbf (2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl) group protects the guanidine side chain of arginine, preventing unwanted side reactions. Its application is crucial in the production of peptides for research, pharmaceuticals, and biotechnology, where precise sequence control is essential. It is particularly valuable in synthesizing peptides with D-amino acids, which are often used to enhance stability and bioavailability in therapeutic peptides.
Sizes / Availability / Pricing:
Size (g) | Availability | Price | Quantity |
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1.000 | 10-20 days | $71.43 |
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5.000 | 10-20 days | $285.73 |
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Fmoc-D-Arg(Pbf)-OH
This chemical is widely used in peptide synthesis, particularly in solid-phase peptide synthesis (SPPS) methods. It serves as a building block for introducing D-arginine residues into peptide sequences. The Fmoc (fluorenylmethyloxycarbonyl) group acts as a protecting group for the amino group, ensuring selective reactions during peptide chain assembly. The Pbf (2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl) group protects the guanidine side chain of arginine, preventing unwanted side reactions. Its application is crucial in the production of peptides for research, pharmaceuticals, and biotechnology, where precise sequence control is essential. It is particularly valuable in synthesizing peptides with D-amino acids, which are often used to enhance stability and bioavailability in therapeutic peptides.
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