cis-4-Azido-N-(tert-butoxycarbonyl)-L-proline
≥98%
- Product Code: 76649
CAS:
132622-65-2
| Molecular Weight: | 256.26 g./mol | Molecular Formula: | C₁₀H₁₆N₄O₄ |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD04115791 | |
| Melting Point: | Boiling Point: | ||
| Density: | Storage Condition: | 2-8°C |
Product Description:
This chemical is primarily used in peptide synthesis and bioconjugation processes. It serves as a protected form of proline, where the tert-butoxycarbonyl (Boc) group safeguards the amino functionality, allowing selective reactions at other sites. The azido group enables click chemistry, particularly in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions, which are widely employed in labeling, crosslinking, or modifying biomolecules. Its cis configuration can influence the conformational properties of peptides, making it valuable in designing bioactive compounds or studying protein structures. Additionally, it is utilized in the development of prodrugs, peptide-based therapeutics, and materials for drug delivery systems due to its compatibility with various organic transformations.
Product Specification:
| Test | Specification |
|---|---|
| APPEARANCE | White to Almost white powder to crystal |
| PURITY | 98-100 |
| MELTING POINT | 69.0-73.0 |
| Infrared spectrum | Conforms to Structure |
| Specific rotation a20DC1 Methanol | -23.0 |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.050 | 10-20 days | ฿2,450.00 |
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cis-4-Azido-N-(tert-butoxycarbonyl)-L-proline
This chemical is primarily used in peptide synthesis and bioconjugation processes. It serves as a protected form of proline, where the tert-butoxycarbonyl (Boc) group safeguards the amino functionality, allowing selective reactions at other sites. The azido group enables click chemistry, particularly in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions, which are widely employed in labeling, crosslinking, or modifying biomolecules. Its cis configuration can influence the conformational properties of peptides, making it valuable in designing bioactive compounds or studying protein structures. Additionally, it is utilized in the development of prodrugs, peptide-based therapeutics, and materials for drug delivery systems due to its compatibility with various organic transformations.
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