ABT-737

≥97%

  • Product Code: 77432
  CAS:    852808-04-9
Molecular Weight: 813.43 g./mol Molecular Formula: C₄₂H₄₅ClN₆O₅S₂
EC Number: MDL Number:
Melting Point: 148-151° C Boiling Point:
Density: Storage Condition: -20°C
Product Description: ABT-737 is primarily used in research settings to study apoptosis, or programmed cell death, in cancer cells. It functions as a potent inhibitor of Bcl-2 family proteins, which are often overexpressed in various cancers to prevent cell death. By blocking these proteins, ABT-737 promotes apoptosis in cancer cells, making it a valuable tool for understanding cancer biology and developing potential therapeutic strategies. It is also used in preclinical studies to evaluate its efficacy in combination with other anticancer agents, providing insights into synergistic effects and resistance mechanisms. Additionally, ABT-737 helps researchers explore the role of Bcl-2 family proteins in other diseases where apoptosis regulation is disrupted.
Product Specification:
Test Specification
APPEARANCE Faint Yellow to Yellow Crystals or Flakes
PURITY 97-100
NMR Consistent with structure
Infrared spectrum Conforms to Structure
Sizes / Availability / Pricing:
Size (g) Availability Price Quantity
0.005 10-20 days ฿5,180.00
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-
0.025 10-20 days ฿14,940.00
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-
ABT-737
ABT-737 is primarily used in research settings to study apoptosis, or programmed cell death, in cancer cells. It functions as a potent inhibitor of Bcl-2 family proteins, which are often overexpressed in various cancers to prevent cell death. By blocking these proteins, ABT-737 promotes apoptosis in cancer cells, making it a valuable tool for understanding cancer biology and developing potential therapeutic strategies. It is also used in preclinical studies to evaluate its efficacy in combination with other anticancer agents, providing insights into synergistic effects and resistance mechanisms. Additionally, ABT-737 helps researchers explore the role of Bcl-2 family proteins in other diseases where apoptosis regulation is disrupted.
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