2-Pyridinesulfonyl Fluoride
≥98%
- Product Code: 79696
CAS:
878376-35-3
| Molecular Weight: | 161.15 g./mol | Molecular Formula: | C₅H₄FNO₂S |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD09265513 | |
| Melting Point: | Boiling Point: | 234.939ºC | |
| Density: | 1.421g/cm3 | Storage Condition: | room temperature, dry |
Product Description:
2-Pyridinesulfonyl fluoride is primarily used in organic synthesis as a versatile reagent, particularly in the modification of biomolecules. It is widely employed in chemical biology and medicinal chemistry for the selective labeling of proteins and peptides. The compound acts as a reactive electrophile, enabling the introduction of sulfonyl fluoride groups into target molecules, which can then be further functionalized or studied. Its application extends to the development of covalent inhibitors, where it forms stable bonds with amino acid residues, such as serine, threonine, or tyrosine, in enzyme active sites. This property makes it valuable in drug discovery and proteomics research for identifying and characterizing protein interactions. Additionally, it is utilized in the synthesis of complex organic molecules, where its sulfonyl fluoride group serves as a key intermediate in various transformations.
Product Specification:
| Test | Specification |
|---|---|
| APPEARANCE | White to off-white (<29 |
| PURITY | 97.5-100 |
| Infrared spectrum | Conforms to Structure |
| NMR | Conforms to Structure |
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.250 | 10-20 days | ฿710.00 |
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| 1.000 | 10-20 days | ฿1,360.00 |
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2-Pyridinesulfonyl Fluoride
2-Pyridinesulfonyl fluoride is primarily used in organic synthesis as a versatile reagent, particularly in the modification of biomolecules. It is widely employed in chemical biology and medicinal chemistry for the selective labeling of proteins and peptides. The compound acts as a reactive electrophile, enabling the introduction of sulfonyl fluoride groups into target molecules, which can then be further functionalized or studied. Its application extends to the development of covalent inhibitors, where it forms stable bonds with amino acid residues, such as serine, threonine, or tyrosine, in enzyme active sites. This property makes it valuable in drug discovery and proteomics research for identifying and characterizing protein interactions. Additionally, it is utilized in the synthesis of complex organic molecules, where its sulfonyl fluoride group serves as a key intermediate in various transformations.
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