(R)-3-(3-Fluoro-4-thiomorpholinophenyl)-5-(hydroxymethyl)oxazolidin-2-one
95%
- Product Code: 82096
CAS:
168828-72-6
| Molecular Weight: | 312.36 g./mol | Molecular Formula: | C₁₄H₁₇FN₂O₃S |
|---|---|---|---|
| EC Number: | MDL Number: | MFCD08234639 | |
| Melting Point: | 135-136 °C | Boiling Point: | 520.1±50.0 °C(Predicted) |
| Density: | 1.381±0.06 g/cm3(Predicted) | Storage Condition: | room temperature |
Product Description:
This compound is primarily utilized in the development of pharmaceutical agents, particularly as a key intermediate in the synthesis of antibiotics. Its structure is critical in the creation of oxazolidinone-based drugs, which are effective against Gram-positive bacterial infections, including those resistant to other antibiotics. The presence of the thiomorpholine and fluorine groups enhances its binding affinity to bacterial ribosomes, thereby improving its efficacy in inhibiting protein synthesis in pathogens. This makes it valuable in addressing complex infections such as methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE). Additionally, its hydroxymethyl group contributes to its solubility and bioavailability, making it a promising candidate for further drug optimization and therapeutic applications.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.100 | 10-20 days | ฿14,040.00 |
+
-
|
| 0.250 | 10-20 days | ฿24,570.00 |
+
-
|
| 1.000 | 10-20 days | ฿49,140.00 |
+
-
|
(R)-3-(3-Fluoro-4-thiomorpholinophenyl)-5-(hydroxymethyl)oxazolidin-2-one
This compound is primarily utilized in the development of pharmaceutical agents, particularly as a key intermediate in the synthesis of antibiotics. Its structure is critical in the creation of oxazolidinone-based drugs, which are effective against Gram-positive bacterial infections, including those resistant to other antibiotics. The presence of the thiomorpholine and fluorine groups enhances its binding affinity to bacterial ribosomes, thereby improving its efficacy in inhibiting protein synthesis in pathogens. This makes it valuable in addressing complex infections such as methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant enterococci (VRE). Additionally, its hydroxymethyl group contributes to its solubility and bioavailability, making it a promising candidate for further drug optimization and therapeutic applications.
| Mechanism | - |
| Appearance | - |
| Longevity | - |
| Strength | - |
| Storage | - |
| Shelf Life | - |
| Allergen(s) | - |
| Dosage (Range) | - |
| Recommended Dosage | - |
| Dosage (Per Day) | - |
| Recommended Dosage (Per Day) | - |
| Mix Method | - |
| Heat Resistance | - |
| Stable in pH range | - |
| Solubility | - |
| Product Types | - |
| INCI | - |
Cart
No products
Subtotal:
฿0.00
฿0.00
Total :