DOTA-Biotin-Sarcosine
98%
- Product Code: 86913
CAS:
180978-54-5
| Molecular Weight: | 806.93 g./mol | Molecular Formula: | C₃₆H₅₄N₈O₁₁S |
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| Density: | Storage Condition: | Room temperature, sealed, dry |
Product Description:
DOTA-Biotin-Sarcosine is widely used in the field of molecular imaging and targeted drug delivery. Its application is particularly prominent in the development of radiopharmaceuticals, where it serves as a bifunctional chelator. The DOTA moiety allows for the stable binding of radioactive metal ions, such as gadolinium or lutetium, which are essential for imaging and therapeutic purposes. The biotin component facilitates strong and specific interactions with avidin or streptavidin, enabling precise targeting of cancer cells or other biological markers. This makes it valuable in techniques like positron emission tomography (PET) and single-photon emission computed tomography (SPECT) for diagnostic imaging. Additionally, it is utilized in pretargeting strategies to enhance the efficacy of radiotherapy while minimizing damage to healthy tissues. Its sarcosine component further improves solubility and pharmacokinetics, making it a versatile tool in biomedical research and clinical applications.
Sizes / Availability / Pricing:
| Size (g) | Availability | Price | Quantity |
|---|---|---|---|
| 0.001 | 10-20 days | ฿16,335.00 |
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DOTA-Biotin-Sarcosine
DOTA-Biotin-Sarcosine is widely used in the field of molecular imaging and targeted drug delivery. Its application is particularly prominent in the development of radiopharmaceuticals, where it serves as a bifunctional chelator. The DOTA moiety allows for the stable binding of radioactive metal ions, such as gadolinium or lutetium, which are essential for imaging and therapeutic purposes. The biotin component facilitates strong and specific interactions with avidin or streptavidin, enabling precise targeting of cancer cells or other biological markers. This makes it valuable in techniques like positron emission tomography (PET) and single-photon emission computed tomography (SPECT) for diagnostic imaging. Additionally, it is utilized in pretargeting strategies to enhance the efficacy of radiotherapy while minimizing damage to healthy tissues. Its sarcosine component further improves solubility and pharmacokinetics, making it a versatile tool in biomedical research and clinical applications.
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